Medical indications: adults with anatomic or functional asplenia
or terminal complement component deficiencies.
Yersiniae have an impaired iron metabolism, and for this reason, they rarely cause sepsis in patients without iron overload, which is often secondary to alcoholism, asplenia
, hemochromatosis, thalassemia major, or tobacco smoking (1).
In response to an audience question, he described doxycycline as "an important and underutilized option" for respiratory tract infections in younger patients--say, those aged 15-50--without comorbid conditions or other significant risk factors for resistant infection, such as having kids in day care chronic renal insufficiency, asplenia
, or a recent history of [beta]-lactam therapy.
, pregnancy, diabetes, immunodeficiency, HIV infection, hepatitis exposures) may be found elsewhere (12).
The population of immunocompromised patients is large and growing; many have asplenia
or solid organ or bone marrow transplants (26).
The "other" category included children with congenital anomalies such as congenital heart or lung defects, children with anatomic asplenia
, and children on immunosuppressive medication regimens.
Accordingly persons who have hemochromatosis, alcoholism, or asplenia
are advised to [ILLEGIBLE TEXT] prompt antibiotic therapy if they are exposed to a dog bite (31).
PCV13 is now recommended for adults 19 years and older who have immunocompromising conditions such as chronic renal failure, functional or anatomic asplenia
, cerebrospinal fluid leaks, or cochlear implants.
The Centers for Disease Control and Prevention (CDC) recommends meningococcal vaccination in a two-dose series for infants and children 9 through 23 months of age who are at high risk for meningococcal disease, including those travelling to countries where meningococcal infection is hyperendemic orendemic, those with persistent complement component deficiency, or functional or anatomic asplenia
, and children who are in a defined risk group during a community or institutional meningococcal disease outbreak.
Persons with asplenia
and complement deficiency should receive a booster every 5 years.
Her medical history was significant for hetorotaxia syndrome with a single left ventricle, double-outlet right ventricle, AV-valve regurgitation, small bicuspid pulmonary valve with stenosis, asplenia
, and GERD.
failure or nephrotic syndrome, functional or anatomic asplenia