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Invasive aspergillosis is a life-threatening fungal infection predominantly occurring in immunocompromised patients, including those with cancer, particularly leukemias," said Bernie Zeiher, M.
Aspergillosis due to voriconazole highly-resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles.
In the SECURE study (a study of 516 patients), CRESEMBA demonstrated non-inferiority to voriconazole on the primary endpoint of all-cause mortality at day 42 for the treatment of adult patients with invasive aspergillosis or other filamentous fungi.
Voriconazole and posaconazole improve asthma severity in allergic bronchopulmonary aspergillosis and severe asthma with fungal sensitization.
Although AMB is one of the most preferred agents for invasive aspergillosis management, its poor bone penetration and renal toxicity can require the choice of alternative antifungal agents for osteomyelitis, especially in pediatric patients.
Increased antigen-specific Th-2 response in allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis.
Aspergillosis can be a killer in humans with weak immune systems.
Vaccinated mice were able to survive high doses of Aspergillus - the fungus that causes aspergillosis.
Becky developed Aspergillosis because she has cystic fibrosis.