aseptic necrosis

necrosis /ne·cro·sis/ (nĕ-kro´sis) pl. necro´ses   [Gr.] the morphological changes indicative of cell death caused by progressive enzymatic degradation; it may affect groups of cells or part of a structure or an organ.

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aseptic necrosis  necrosis without infection, usually in the head of the femur after traumatic hip dislocation.

Balser's fatty necrosis  gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues.

caseous necrosis  cheesy n.

central necrosis  that affecting the central portion of an affected bone, cell, or lobule of the liver.

cheesy necrosis  that in which the tissue is soft, dry, and cottage cheese–like; most often seen in tuberculosis and syphilis.

coagulation necrosis  necrosis of a portion of some organ or tissue, with formation of fibrous infarcts, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.

colliquative necrosis  that in which the necrotic material becomes softened and liquefied.

contraction band necrosis  a cardiac lesion characterized by hypercontracted myofibrils and contraction bands and mitochondrial damage, caused by calcium influx into dying cells resulting in arrest of the cells in the contracted state.

fat necrosis  that in which the neutral fats in adipose tissue are split into fatty acids and glycerol, usually affecting the pancreas and peripancreatic fat in acute hemorrhagic pancreatitis.

liquefaction necrosis  colliquative n.

phosphorus necrosis  necrosis of the jaw bone due to exposure to phosphorus.

postpartum pituitary necrosis  necrosis of the pituitary during the postpartum period, often associated with shock and excessive uterine bleeding during delivery, and leading to variable patterns of hypopituitarism.

subcutaneous fat necrosis  induration of the subcutaneous fat in newborn and young infants.

necrosis ustilagi´nea  dry gangrene due to ergotism.

Zenker's necrosis  see under degeneration.

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aseptic necrosis

n.

Necrosis occurring in the absence of infection.

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aseptic necrosis

Etymology: Gk, a, sepsis, without decay, nekros, dead, osis, condition

cystic and sclerotic degenerative changes in tissues. A condition in which poor blood supply to an area of bone leads to bone death. It may follow an injury in the absence of infection. See also avascular necrosis, osteonecrosis.

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necrosis [nĕ-kro´sis, ne-kro´sis] (Gr.)

the morphological changes indicative of cell death caused by enzymatic degradation.

aseptic necrosis necrosis without infection or inflammation.

acute tubular necrosis acute renal failure with mild to severe damage or necrosis of tubule cells, usually secondary to either nephrotoxicity, ischemia after major surgery, trauma (see crush syndrome), severe hypovolemia, sepsis, or burns. See also lower nephron nephrosis.

Balser's fatty necrosis gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues.

bridging necrosis septa of confluent necrosis bridging adjacent central veins of hepatic lobules and portal triads characteristic of subacute hepatic necrosis.

caseous necrosis caseation (def. 2).

central necrosis necrosis affecting the central portion of an affected bone, cell, or lobule of the liver.

cheesy necrosis caseation (def. 2).

coagulation necrosis death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.

colliquative necrosis liquefactive necrosis.

fat necrosis necrosis in which fat is broken down into fatty acids and glycerol, usually occurring in subcutaneous tissue as a result of trauma.

liquefactive necrosis necrosis in which the necrotic material becomes softened and liquefied.

massive hepatic necrosis massive, usually fatal, necrosis of the liver, a rare complication of viral hepatitis (fulminant hepatitis) that may also result from exposure to hepatotoxins or from drug hypersensitivity.

moist necrosis necrosis in which the dead tissue is wet and soft.

postpartum pituitary necrosis see postpartum pituitary necrosis.

selective myocardial cell necrosis myofibrillar degeneration.

subcutaneous fat necrosis of newborn a benign, self-limited disease affecting term newborns and young infants, characterized by circumscribed, indurated, nodular areas of fat necrosis. It is thought to be related to trauma on bony prominences during delivery, hypothermia, asphyxia, or maternal diabetes; it usually resolves spontaneously by 2 to 4 weeks with no scarring. Called also adiponecrosis neonatorum or subcutanea.

Zenker's necrosis hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration.

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necrosis

pl. necroses [Gr.] the morphological changes indicative of cell death caused by enzymatic degradation.

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aseptic necrosis

necrosis without infection or inflammation.

caseous necrosis

necrosis in which the tissue is soft, dry and cheesy, occurring typically in tuberculosis.

central necrosis

necrosis affecting the central portion of an affected bone, cell or lobule of the liver.

cheesy necrosis

that in which the tissue resembles cottage cheese; most often seen in tuberculosis.

coagulation necrosis

death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.

colliquative necrosis

see liquefactive necrosis (below).

liquefactive necrosis

necrosis in which the necrotic material becomes softened and liquefied.

moist necrosis

necrosis in which the dead tissue is wet and soft.

Zenker's necrosis

hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration.

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aseptic necrosis

Avascular necrosis, osteonecrosis Orthopedics Death of bony tissue, usually due to ischemia. See Necrosis.