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ASCUS

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.02 sec.
as·cus (sks)
n. pl. as·ci (s, -k)
A membranous, often club-shaped structure in which typically eight spores are formed through sexual reproduction of ascomycetes.

ascus
pl. asci; the spore case of Ascomycetes.

ASCUS
Atypical squamous cell of undetermined significance Cytology A cell seen in a pap smear of the cervix that fulfills some of the criteria–eg nuclear enlargement and irregularity, cytoplasmic clearing, and thickened cell membranes, that define cells typical of either a condyloma or a neoplasm. See CIN, HSIL, LSIL. Cf AGUS, SIL.


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HPV genotyping may be important to assessing the risk of developing pre-cancerous conditions or cervical cancer in women with either ASCUS (an ambiguous type of cellular abnormality formally called "atypical squamous cells of undetermined significance") or LSIL (mildly abnormal cells formally called "low-grade squamous intraepithelial lesions") results of Pap testing.
Another study conducted in Europe, "Validation of the ThinPrep Imaging System: A Multi-Center European Study," presented data showing that cytotechnologists using the ThinPrep Imaging System are more effective than Manual review for the detection of ASCUS and more severe cervical abnormalities.
Digene Corporation (Nasdaq: DIGE) and Cytyc Corporation (Nasdaq: CYTC) today announced that the American Medical Women's Association (AMWA) has developed new patient guidelines that recommend testing for human papillomavirus (HPV) for the millions of women each year who receive abnormal results known as ASCUS following their routine Pap test.
 
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