ascus


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ascus

 [as´kus]
the spore case of certain fungi.

ASCUS

In the Bethesda system, acronym for atypical squamous cells of undetermined significance , under cell.
See also: Bethesda system.

as·cus

, pl.

as·ci

(as'kŭs, as'ī),
The saclike cell of Ascomycetes in which ascospores develop following nuclear fusion and meiosis.
[G. askos, bag]

ASCUS

Atypical squamous cell of undetermined significance Cytology A cell seen in a pap smear of the cervix that fulfills some of the criteria–eg nuclear enlargement and irregularity, cytoplasmic clearing, and thickened cell membranes, that define cells typical of either a condyloma or a neoplasm. See CIN, HSIL, LSIL. Cf AGUS, SIL.

ASCUS

Abbreviation for atypical squamous cells of undetermined significance.
Ascusclick for a larger image
Fig. 50 Ascus . An ascus containing ascospores of Neurospora crassa.

ascus or (formerly) theca

(pl. asci) a cell present in the fruiting body of ASCOMYCETE fungi in which the fusion of HAPLOID nuclei occurs during sexual reproduction. This is normally followed by MEIOSIS, giving rise to four haploid cells, after which MITOSIS produces eight ASCOSPORES. The precise arrangement of ascospores within the ascus enables the events at meiosis to be fully analysed (see TETRAD ANALYSIS). The asci are usually enclosed within an aggregation of hyphae termed an ASCOCARP, a number of different types being recognized, e.g. perithecium, cleistothecium, apothecium.

ascus

pl. asci; the spore case of Ascomycetes.
References in periodicals archive ?
The presence of oncogenic HPV in the context of ASCUS cytology is a better predictor of progression to either LSIL or HSIL than the diagnosis of ASC-H alone," Dr.
If ASCUS is associated with severe inflammation and a specific infectious agent is identified, reevaluation should be performed after appropriate treatment.
Food and Drug Administration (FDA) approved the use of High-Risk Hybrid Capture II HPV DNA testing, developed by Digene Corporation, as a follow-up for patients with ASCUS results on their Pap tests.
Evan Jones, Digene's Chairman and Chief Executive Officer, said, "These new results from the ALTS trial underscore why HPV testing is increasingly becoming the standard of care among physicians in managing the over two million women each year who are faced with ASCUS Pap results.
7% without abnormal cytologic results Betancourt (19) Sensitivity 93% for ASCUS, low- or high- grade AIN, or SCC; sensitivity 84% for low-grade AIN; sensitivity 20% for high- grade AIN or SCC AIN, anal intraepithelial neoplasia; ASCUS, atypical squamous cells of unknown significance; MSM, men who have sex with men; SCC, squamous cell carcinoma; SIL, squamous intraepithelial lesions.
Healthy non-smoking women under the age of 30 with ASCUS or LSIL are likely to see a subsequent normal Pap result.
Cytological abnormality age-specific prevalence percentage (95% CI) Age group N Cytology abnormal ASCUS <25 102 16.
Prevalence and typing of HPV DNA by hybrid capture II in women with ASCUS, ASC-H, LSIL, and AGC on ThinPrep Pap tests.
Women 21-29 years of age--obtain annual smears with HPV reflex test if result indicates ASCUS until the age of 30.
Cytology with use of HPV testing to triage ASCUS cytology (every 1-3 years) (cytology+HPV triage);