arylsulfatase


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ar·yl·sul·fa·tase

(ar'il-sŭl'fă-tās),
An enzyme that catalyzes the hydrolysis of phenol sulfates, including cerebroside sulfates (that is, a phenol sulfate + H2O → a phenol + sulfate anion). Some arylsulfatases are inhibited by sulfate (type II) and some are not (type I).
Synonym(s): sulfatase (2)

ar·yl·sul·fa·tase

(ar'il-sŭl'fă-tās)
An enzyme that cleaves phenol sulfates, including cerebroside sulfates (i.e., a phenol sulfate + H2O → a phenol + sulfate anion). Some arylsulfatases are inhibited by sulfate (type II) and some are not (type I).
Synonym(s): sulfatase (2) , arylsulphatase.

arylsulfatase

a group of enzymes active in the hydrolysis of sulfates and the metabolism of mucopolysaccharides; found in liver, pancreas, kidneys and immature monocytes. Several species of molluscs and Aerobacter spp. serve as commercial sources of the enzyme which is used in analytic endocrinology.

arylsulfatase A deficiency
see metachromatic leukodystrophy.
arylsulfatase B deficiency
is the cause of mucopolysaccharidosis VI which occurs in humans and cats. Called also Maroteaux-Lamy syndrome.
References in periodicals archive ?
Arylsulfatase activity was weakly positive at 3 days and positive at 14 days.
b) Arylsulfatase B: IT, 20 h; EL, 30 [micro]L of distilled water and 20 [micro]L of 15 mmol/L lead acetate in sodium acetate buffer (0.
SHP611 is in development as recombinant human arylsulfatase A (rASA) delivered intrathecally every other week for the treatment of the late infantile form of MLD.
Moreover, the 3 genomes we identified contain homologs of arylsulfatase and genes that enable invasion of brain endothelial cells, which contribute to the ability of Escherichia coli to cross the blood-brain barrier in neonatal meningitis (32).
Urease, L-glutaminase, L-asparaginase, alkaline phosphomonoesterase, and arylsulfatase activities were determined in the rhizospheric soil according to the protocols described by Tabatabai [16, 17].
DSM's patent application for Maxilact[R] lactase, which is free from arylsulfatase, has been granted in Europe.
The activities of the enzymes arylsulfatase, [beta]-glucosidase, leucine-aminopeptidase, and acid and alkaline phosphatase were determined upon applying an extraction-desorption procedure (Fornasier and Margon 2007) and using fluorescent analogues of each enzyme's substrate on microplates.
Rapid method for measuring arylsulfatase A and B in leucocytes as a diagnosis for sulfatidosis, mucosulfatidosis and mucopolysaccharidosis VI.
The enzymatic activity in terms of P-Glucuronidase and Arylsulfatase from the kidney and liver were determined as these enzymes are responsible for the conjugation reactions.
0, followed by hydrolysis with [beta]-glucuronidase and arylsulfatase (HP-2; Sigma-Aldrich, Inc.
Genetic abnormalities on chromosomes 22 or 10 result in deficiencies in the lysosomal enzyme arylsulfatase A or prosapisine, respectively, which leads to myelin breakdown.