artificial skin


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Any synthetic material designed to replace skin lost through burns or trauma, which ideally would have the physicochemical properties of skin—e.g., optimal ‘wetting’ and ‘draping’—leading to adherence, decreased bacterial invasion and fluid loss, eliciting cellular and vascular invasion, and synthesising a dermal matrix while biodegrading the artificial graft

artificial skin

Critical care Any synthetic material designed to have the physicochemical properties of skin–eg, optimal 'wetting' and 'draping,' leading to adherence, ↓ bacterial invasion and fluid loss, eliciting cellular and vascular invasion, synthesizing a dermal matrix while biodegrading the artificial graft. See Burns, Dermagraft-TC, Integra Artificial Skin. Cf Split-thickness graft, Spray-on-skin.

skin

(skin)
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STRUCTURE OF THE SKIN AND SUBCUTANEOUS TISSUE
The organ that forms the outer surface of the body. It shields the body against infection, dehydration, and temperature changes; provides sensory information about the environment; manufactures vitamin D; and excretes salts and small amounts of urea.

Skin consists of two major divisions: the epidermis and the dermis. Depending on its location and local function, skin varies in terms of its thickness, strength, presence of hair, nails, or glands, pigmentation, vascularity, nerve supply, and keratinization. Skin may be classified as thin and hairy or thick and hairless (glabrous). Thin hairy skin covers most of the body. Glabrous skin covers the surface of the palms of the hands, soles of the feet, and flexor surfaces of the digits. See: illustration; hair for illus; burn; dermatitis; dermis; eczema; epidermis; rash

alligator skin

Severe scaling of the skin with formation of thick plates resembling the hide of an alligator. See: ichthyosis

artificial skin

Human skin equivalent.

bronzed skin

Brownish hyperpigmentation of the skin, seen in Addison's disease and hemochromatosis, some cases of diabetes mellitus, and cirrhosis.

deciduous skin

Keratolysis.

elastic skin

Ehlers-Danlos syndrome.

foreign bodies in the skin

Objects that enter the skin accidentally or are inserted deliberately. The areas involved are cleaned carefully. Foreign material can be removed carefully piece by piece or by vigorous swabbing with gauze or a brush and a soapy solution. A sterile dressing should be used.

For removal of a small foreign body, the area is cleaned first with mild soap and warm water. A clean needle can be sterilized by heating it to a dull or bright red in a flame; this can be done with a single match. Because both ends of the needle get hot, it is wise to hold the far end in a nonconductor such as a fold of paper or a cork. The needle is allowed to cool. A black deposit on its surface should be disregarded; it is sterile carbon and does not interfere with the procedure. The needle is introduced at right angles to the direction of the sliver, and the sliver is lifted out. Most people attempt to stick the needle in the direction of the foreign body and consequently thrust many times before they manage to lift the sliver out. When the sliver is removed, an antiseptic is applied and the wound covered with a sterile dressing. Tetanus antitoxin or a tetanus booster may be required, depending on the history of immunization.

glabrous skin

Skin that does not contain hair follicles, such as that over the palms and soles.

glossy skin

Shiny appearance of the skin due to atrophy or injury to nerves.

hidebound skin

Scleroderma.

loose skin

Hypertrophy of the skin.

parchment skin

Atrophy of the skin with stretching.

photoaged skin

Skin changes caused by chronic sun exposure. This condition is prevented by avoiding suntanning and sunburning and has been treated with topical tretinoin and chemical peels.
Synonym: photodamaged skin

photodamaged skin

Photoaged skin.

piebald skin

Vitiligo.

scarf skin

The cuticle, epidermis; the outer layer of the skin.

sun-damaged skin

Photoaged skin.

tissue-engineered skin

Human skin equivalent.

true skin

Dermis.
References in periodicals archive ?
A second market for this promoter is the field of artificial skin development.
of Histology at the University of Granada, have managed, for the first time, to grow artificial skin from stem cells of umbilical cord.
In this version, the sandwich's middle was a flat rubber film that wasn't so sensitive, but combining the technologies and spotting the resulting sandwiches onto another material could yield sensitive, stretchable artificial skin.
Made of scales of artificial skin, the tail ended in a tuft of horsehair, which the artist caused to move at great effort (due N) its length).
This gel has numerous far-reaching applications, such as artificial skin that could be sensory -- a holy grail in robotics.
Surgeons at the Chelsea and Westminster Hospital in West London removed all the skin from her face and used an artificial skin before rebuilding it with grafts from other parts of her body.
The farmer here, Ted Fink, was burned over 93 percent of his body and required his wife, Rhoda, to make horrendous decisions alone, choosing to use artificial skin to save his life while he was in a coma for six months.
Plastic surgeons at Newcastle's Royal Victoria Infirmary use an artificial skin template, made from the fin, to help repair patients with the most serious and deepest burns.
Staff used special artificial skin made out of shark cartilage to help minimise the scarring effect of burns and to help reduce healing time.
He went on: 'We were able, over a 48-hour period, to cover her whole body with an artificial skin replacement that allowed this to start healing rapidly.
Because they meet medical guidelines for critical design, component tolerance and sterilizability, plastic polymers will aid in the production of artificial hearts, artificial bones, artificial skin and artificial organs.
And skin was also used within the trust to test healing and artificial skin techniques.