artificial oxygen carriers

artificial oxygen carriers

Synthetic solutions capable of carrying and unloading oxygen, that can safely be administered intravenously to improve the oxygenation of tissues. Substances such as perfluorocarbons can be emulsified and infused and are capable of working in the manner of haemoglobin. When the technology and safety has been fully established, artificial oxygen carriers are expected to make an important contribution to solving the discrepancy between demand and supply of blood for transfusion.
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of Monterrey, Mexico, and SanguiBioTech GmbH, Witten, Germany, will jointly promote the FDA authorization of Sangui's artificial oxygen carriers as blood additive.
The respiration sensors of GlukoMediTech AG have been developed for research with artificial oxygen carriers, the main product of its sister company SanguiBioTech AG, Witten, explained Kai Zirk, chief technology officer and director of research & development for GlukoMediTech AG since September.
There he spent years evaluating artificial oxygen carriers in small animal models such as the magneto metric determination of the impairment of the body's own macrophages that are responsible for detoxification.
Sangui is engaged in the development of novel products with the focus on artificial oxygen carriers for pharmaceutical and cosmetic application, and glucose sensors for the continuous monitoring of a diabetes patient's glucose level.
The SanguiBioTech AG in Witten works intensely on the development of artificial oxygen carriers on the basis of pig hemoglobin that -- by application into the blood as an additive -- is intended to improve the oxygen supply of tissue and organs in the body, and on the development of a blood volume substitute that will be used after heavy blood losses.
SanguiBioTech AG has been developing artificial oxygen carriers on the basis of porcine hemoglobin.
With the new manufacturing process it is possible to manufacture with a very high yield artificial oxygen carriers with good functional properties for both types of applications simultaneously," said Professor Wolfgang Barnikol, MD, PhD, Chief Executive Officer of SanguiBioTech AG and Chief Executive Officer/President of Sangui BioTech International Inc.
They create the prerequisites for carrying out tests on the effectiveness and tolerance of the artificial oxygen carriers and the permanently implanted glucose sensors, the two main development projects of the company.
Further, the company's measuring techniques will be demonstrated, which are used for determination of the oxygen binding characteristics, of the colloid-osmotic pressure and of the viscosity of the artificial oxygen carriers.
SanguiBioTech AG is engaged in the research and development of artificial oxygen carriers based on native hemoglobin to be used as blood substitutes in case of acute blood loss and as blood additives.