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arteriosclerosis obliterans

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Hutchinson 0.02 sec.
arteriosclerosis /ar·te·rio·scle·ro·sis/ (-sklĕ-ro´sis) a group of diseases characterized by thickening and loss of elasticity of the arterial walls, occurring in three forms: atherosclerosis, Mönckeberg's arteriosclerosis, and arteriolosclerosis.arteriosclerot´ic
Mönckeberg's arteriosclerosis  arteriosclerosis with extensive deposits of calcium in the middle coat of the artery.
arteriosclerosis obli´terans  that in which proliferation of the intima of the small vessels has caused complete obliteration of the lumen of the artery.
peripheral arteriosclerosis  arteriosclerosis of the limbs.

arteriosclerosis o·blit·er·ans (-blt-rnz)
n.
Arteriosclerosis producing narrowing and occlusion of the arterial lumen.

arteriosclerosis obliterans
Etymology: Gk, arteria + skleros + L, obliterare, efface
a gradual narrowing of the arteries with thrombosis and degeneration of the intima. The condition may lead to complete occlusion of an artery and subsequent gangrene.


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In Japan, the two companies are currently conducting phase II clinical studies of NM-702 for the treatment of intermittent claudication caused by arteriosclerosis obliterans and lumber spinal canal stenosis as well as bronchial asthma.
Pathological studies have demonstrated that 70% of BFD patients have histologic lesions compatible with the changes of arteriosclerosis obliterans and 30% with the changes of thromboangiitis obliterans (Yeh and How 1963).
Pathologically, BFD is compatible with thromboangiitis obliterans and arteriosclerosis obliterans (12,13).
 
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