falciparum sitmasi olgusundan yedisinde artemisin
, kalan altisinda kinin iceren tedavi verildigi bildirilmektedir (5, 9-11).
Different methodological approaches to the assessment of invivo efficacy of three artemisin
in-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.
The natural compound artemisin
comes from the sweet wormwood plant and can fight drug-resistant malaria, but due to its small quantities and high price, millions of people cannot get access to this remedy.
A research team at University of California, Berkeley developed a process to produce arteminisinic acid and Amyris Biotechnologies developed a production process for artemisin
The WHO publication, Guidelines on Cultivating Essential Plants Used in Anti-Malaria Medicines describes in detail how to grow Artemisia Annua and importantly, how to plan production of its essential products and extract artemisin
from the dried leaves.
Alkylation of human albumin by the antimalarial artemisin
Besides the flavonoide p7F, artemisin
and its metabolite artesunate present in wormwood, though in very small amounts, may also have played a role in the observed effect of this herb.
Close collaboration between the pharmaceutical sector, WHO, and the Chinese government resulted in the development of the antimalarial drug artemisin