artemether


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ar·te·me·ther

(ar-tem'ĕ-ther),
Semisynthetic derivative of artemisinin used in the treatment of malaria.

artemether

A semi-synthetic derivative of ARTEMISININ. The drug is on the WHO official list.
References in periodicals archive ?
This compound and its semisynthetic derivatives artemether (2) and artheether (3) are established drugs to combat infections with Plasmodium falciparum and Plasmodium vivax (Tu, 2011).
The >7 days earlier recrudescence for F32-ART5 exposed to artemether compared with that for F32-TEM was not significant because of small numbers of pairedsample experiments.
Resistance of Plasmodium falciparum field isolates to in vitro artemether and point mutations of the SERCA-type PfATpase6.
Antischistosomal activity of artemether in experimental Schistosomiasis mansoni.
artemether, artesunate, and dihydroartemisinin) are associated with a high rate of recrudescences after monotherapy, probably because of the pharmacodynamic properties of these agents (58).
The treatment for malaria in young infants and children uniquely uses a multiple dose spray device for the sublingual delivery of a formulation called ArTiMist, which contains the drug Artemether.
94), and the drugs artesunate and artemether are derivatives known to kill the parasites that cause malaria.
For example, Novartis and Kunming Pharmaceutical signed a General Agreement on Patent Development Permit for the R & D and production of artemether raw materials, U.
Schistosoma mansoni: N-acetylcysteine downregulates oxidative stress and enhances the antischistosomal activity of artemether in mice.
Modification of artemisinin has yielded artemether and arteether (oil soluble derivatives) and dihydroartemisinin (DHA), sodium artesunate and artelinic acid (water soluble derivatives).
Discovery of artemisinin and its derivatives (artesunate, artemether, arteether, and dihydroartemisinin) have given renewed hope for combating resistant malaria (6, 7).