arsphenamine


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ars·phen·a·mine

(ars-fen'ă-min),
A yellow hygroscopic powder formerly used in the treatment of syphilis, yaws, and some other diseases of protozoan origin. The synthesis of arsphenamine in 1907 and the demonstration of its usefulness as a therapeutic agent by Paul Ehrlich and coworkers (1909) marked the beginning of chemotherapy.
Synonym(s): phenarsenamine

arsphenamine

(ärs-fĕn′ə-mēn′)
n.
A drug formerly used to treat syphilis, yaws, and other spirochetal infections.

arsphenamine

(ars-fen′ă-mēn″, -mĕn) [ ars(enic) + phen(yl) + amine]
A light yellow powder containing about 30% arsenic; formerly used in the treatment of syphilis.

arsphenamine

An organic arsenical compound formerly used to treat syphilis. Treatment with arsenical drugs was called arsenotherapy.
References in periodicals archive ?
A biologic is defined as "a virus, therapeutic serum, toxin, antitoxin, vaccine, blood, blood component or derivative, allergenic product, or analogous product, or arsphenamine or derivative of arsphenamine (or any other trivalent organic arsenic compound), applicable to the prevention, treatment, or cure of a disease or condition of human beings.
6) At the time of the Study's inception in 1932, the only prior study of untreated syphilis, the so-called Oslo study, had suggested that non-treated syphilitics had lower rates of morbidity than those who received the standard arsphenamine treatment, which compromised the immune system.
JBH: Patients with early syphilis were given a 3-month course of arsphenamine intravenously weekly, alternated with 3 months of bismuth intramuscularly weekly for a total of 18 months.