arsenic intoxication

arsenic poisoning

Toxicity caused by arsenic, a toxic trace metal that is a key component of herbicides, insecticides, rodenticides, wood preservatives and used in manufacturing glass and paints. The usual fatal dose is 100–200 mg; there are ± 1900 arsenic poisonings/year (US), 85% of which are accidental by children < age 6; the rest are adult suicides.
 
Clinical findings
Vague gastrointestinal (nausea, vomiting) and neurologic (apprehension and shortness of breath) symptoms, and a classic sign—“garlic” breath—followed by dysphagia, tachycardia, severe abdominal pain and bloody diarrhoea, then by renal and cardiac failure and circulatory collapse.
 
Treatment
Dimercaprol (BALS).

arsenic intoxication

Arsenic poisoning A toxic trace metal that is a key component of herbicides, insecticides, rodenticides, wood preservatives, and used in manufacturing glass, and paints; the usual fatal dose is 100–200 mg; there are ± 1900 arsenic intoxications/yr–US, 85% of which are accidental by children < age 6; the rest are adult suicides Clinical Vague GI–N&V and neurologic–apprehension and SOB symptoms, and a classic sign, 'garlic' breath, followed by dysphagia, tachycardia, severe abdominal pain and bloody diarrhea, then by renal and cardiac failure and circulatory collapse Treatment Dimercaprol–BAL. See Heavy metals.
References in periodicals archive ?
9) However, a detailed haematological picture in chronic arsenic intoxication has hardly been reported in toxicological studies.
Also, previous studies revealed that several antioxidant agents significantly protected against tissue damage due to arsenic intoxication [6,7].
MCHC was significantly decreased in the present study with arsenic intoxication, which is in agreement with results of Halder et al.
Arsenic intoxication is known to produce symptoms such as dark gray skin color, wart-like keratosis on palms and soles, Mees bands, acne-like skin eruptions, skin cancer, liver and kidney disease, and cerebral changes.
1,2,5 Diagnosis of arsenic intoxication is often difficult because clinical presentation varies depending on route of exposure, chemical form, dose, and time elapsed since exposure.
Urine samples are more valid for the diagnosis of arsenic intoxication, but these too are influenced and often rise dramatically after a seafood meal.
Chronic oral arsenic intoxication as a possible aetiological factor in idiopathic portal hypertension (non-cirrhotic portal fibrosis) in India.
The development of Bowen's disease has been linked to sunlight exposure, human papilloma virus (HPV), and chronic arsenic intoxication.
Arsenicosis patients in Guizhou show significantly lower MT transcript levels in blood, which may have predisposed this population to arsenic intoxication.
In the Guizhou region, arsenic intoxication is often accompanied with fluorosis (4-8), and thallium exposure is another health concern (9).
Typical signs and symptoms of arsenic intoxication were not found in any study participants.
1981) suggested a neurotoxic potential of arsenic after acute arsenic intoxication of human patients that caused a polyneuropathy with prolonged sensory and motor deficits.