arrestins

arrestins

a family of proteins that bind to the phosphorylated carboxyl-terminal region of serpentine receptors, preventing them from interaction with G proteins and thereby terminating the signal through those receptors.
References in periodicals archive ?
This will open up a new platform for realising the structural basis of the elusive GPCR regulation by arrestins.
Arrestins are expressed proteins that were first described, and are well-known as negative regulators of G protein-coupled receptor (GPCR) signaling (4).
Nonvisual arrestins function as simple scaffolds assembling the MKK4-JNK3alpha2 signaling complex.
Regulation of lipopolysaccharideinduced inflammatory response and endotoxemia by beta arrestins.
Opposing effects of inositol hexakisphosphate on rod arrestin and arrestin2 self-association.
A special section is included in this year's edition on [Beta]-arrestins with topics that include the role of [Beta]-arrestin-mediated signaling in chemotaxis cellular process, their role in regulating signaling by receptor tyrosine kinases (RTKs), and the role of G protein- coupled receptor kinases and arrestins.
Our broadened claims covering arrestins and any active label are now beginning to issue worldwide.
The proteins are, G protein-coupled receptor kinase 2, arrestins 2 and 3, and dynamin.
For cellular immunodetection of [beta]-arrestin, we used a mouse monoclonal antibody that recognizes both arrestin isoforms (BD Bioscience, San Diego CA), and for [beta]-arrestin Western blot detection, an antibody generously provided by R.