I induced oxidative DNA damage associated with glutathione depletion and ERK1/2 activation in human cells.
The paper indicates that regulatory measures that have so far been adopted by national and international agencies may be inadequate in preventing harmful exposure to aristolochic acid
Nearer to home, an epidemic of kidney disease plus cancer affecting thousands of patients in the Danube basin was laid at the door of aristolochic acid
The industrial chemical formaldehyde and a botanical known as aristolochic acids
are listed as known human carcinogens on the updated list.
It is hoped the work will identify exactly how aristolochic acid
causes cells to become cancerous.
For example, aristolochic acid
is not produced in the United States and the federal government has in place an import ban on it.
Dirty Dozen: 12 Supplements to Avoid Name(s) Dangers Regulatory Actions DEFINITELY HAZARDOUS: Documented organ failure or known carcinogenic properties Aristolochic acid
Potent human carcinogen; FDA warning to (Aristolochia, birthwort, kidney failure, consumers and snakeroot, snakeweed, sometimes requiring industry and import sangree root, sangrel, transplant; deaths alert in April serpentary, serpentaria, reported.
They will first develop testing methods for supplements containing ephedrine-type alkaloids and aristolochic acid
After the transplant, analysis of the herbal remedies clearly indicated the presence of aristolochic acid
in 2 of the 6 Chinese herbs ingested.
The plants of the genera Aristolochia and Asarum became the interesting topic for the phytochemical and pharmaceutical researchers since the discovery of aristolochic acid
Washington, August 8 ( ANI ): Scientists have used genome sequencing to prove that traditional Chinese herbal remedy, aristolochic acid
, causes upper urinary tract cancers.
Traces of aristolochic acid
, a chemical often found in Chinese herbal remedies, were also found.