argyria


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Related to argyria: Colloidal silver

argyria

 [ahr-ji´re-ah]
poisoning by silver or its salts; chronic argyria is marked by a permanent ashen-gray discoloration of the skin, conjunctivae, and internal organs, and there is usually a slate blue “silver line” on the gingival margin. Argyria can result from either industrial or medicinal exposure.

ar·gyr·i·a

(ar-jir'ē-ă, -jī'rē-ă),
A slate-gray or bluish discoloration of the skin and deep tissues caused by deposits of insoluble albuminate of silver; occurs after a long period of medicinal administration of a soluble silver salt; formerly fairly common because of the use of proprietary preparations of silver-containing materials in the nose and sinuses.
[G. argyros, silver]

argyria

/ar·gyr·ia/ (ahr-jir´e-ah) poisoning by silver or its salts; chronic argyria is marked by a permanent ashen-gray discoloration of the skin, conjunctivae, and internal organs.

argyria

(är-jîr′ē-ə, -jī′rē-ə)
n.
A slate-gray or bluish discoloration of the skin and deep tissues due to the deposition of silver granules resulting from excessive exposure to silver.

ar·gyr′ic adj.

argyria

[ärjī′rē·ə]
Etymology: Gk, argyros, silver
a permanent dull blue or gray to bronze discoloration of the skin, conjunctiva, and internal organs caused by excessive oral intake of silver salts.
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Argyria

argyria

The deposition of silver salts in the skin secondary to acute high level, or to chronic lower level, exposure to elemental silver, silver dust or silver compounds.

Colloidal silver solutions were abandoned by mainstream medical practitioners in the 1940s; agyria now only occurs in alternative health advocates who consume colloidal silver, mistakenly believing it has some health benefits.
 
Clinical findings, acute
Burning of mouth and throat, vomiting, diarrhoea, collapse, coma, death.
 
Clinical findings, chronic
Permanent blue-bronze discolouration of skin and mucosa, especially of sun-exposed zones.

argyria

Toxicology The deposition of silver salts in skin 2º to acute excess or chronic exposure to low levels Clinical-acute Burning of mouth and throat, vomiting, diarrhea, collapse, coma, death Clinical-chronic Permanent blue-bronze discoloration of skin and mucosa, especially of sun-exposed zones

ar·gyr·ia

, argyrosis (ahr-jirē-a, -jir-ōsis)
A slate-gray or bluish discoloration of the skin and deep tissues due to the deposit of silver, occurring after medicinal administration of a soluble silver salt.
[G. argyros, silver]

argyria

A permanent gray staining of the CONJUNCTIVA or skin resulting from prolonged exposure to silver salts, as in silver nitrate eye drops.

argyria

permanent, ash-grey discoloration of skin, proximal nail areas and conjunctivae due to systemic exposure to silver salts

ar·gyr·ia

, argyrism , argyrosis (ahr-jirē-a, ahrjir-izm, -jir-ōsis)
A slate-gray or bluish discoloration of the skin and deep tissues caused by deposits of insoluble albuminate of silver; occurs after a long period of medicinal administration of a soluble silver salt.
Synonym(s): silver poisoning.
[G. argyros, silver]

argyria

poisoning by silver or its salts; chronic argyria is marked by a permanent ashen-gray discoloration of the skin, conjunctiva and internal organs.
References in periodicals archive ?
Cases of generalized argyria were more prevalent in the first half of the 20th century because of the use of silver-containing compounds as medicinals and increased occupational exposure in the silver industry.
Several recent case reports of argyria from the use of silver-containing products have been described.
Argyria can result in either generalized or localized discoloration of the skin, depending on the route of exposure.
Rosemary Jacobs, a woman who developed argyria as a young girl in the 1950s after using silver-containing nose drops recommended by her physician, has suffered with the condition throughout her life.
The amount of silver needed to cause argyria is not known, but studies using silver to treat syphilis in the preantibiotic era showed a link between argyria and a cumulative dose of intravenous silver arsphenamine that exceeded 4 g intravenously.
Drake and Hazelwood, in their review of the exposure-related health effects of silver and silver compounds, note, "Besides argyria and argyrosis, exposure to soluble silver compounds may produce other toxic effects, including liver and kidney damage, irritation of the eyes, skin, respiratory, and intestinal tract, and changes in blood cells.
Of all the sites included in our study, only 2 (4%) mentioned argyria as a possible complication of colloidal silver, although 30 (61%) did warn against long-term use.
Many of the recent case reports of argyria mention that the patients directly purchased the product over the Internet.
Consumers are unlikely to easily discover the risk of argyria with long-term use of these products.
Ein Fall von Argyria mit Silberabscheidungen im Darm, Leber, Nieren und Milz.