arginase


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Related to arginase: Argininosuccinate

arginase

 [ahr´jĭ-nās]
an enzyme of the liver that splits arginine into urea and ornithine.

ar·gi·nase

(ar'ji-nās),
An enzyme of the liver that catalyzes the hydrolysis of l-arginine to l-ornithine and urea; a key enzyme of the urea cycle. A deficiency of arginase leads to arginemia.
Synonym(s): canavanase

arginase

/ar·gi·nase/ (ahr´jĭ-nās) an enzyme existing primarily in the liver, which hydrolyzes arginine to form urea and ornithine in the urea cycle.

arginase

(är′jə-nās′, -nāz)
n.
An enzyme found primarily in the liver that catalyzes the hydrolysis of arginine to form urea and ornithine.

arginase

[är′jinās]
an enzyme that catalyzes the hydrolysis of arginine during the urea cycle, producing urea and ornithine. The enzyme is found primarily in the liver but also occurs in the mammary gland, testes, and kidney.

ar·gi·nase

(ahr'ji-nās)
An enzyme of the liver that catalyzes the hydrolysis of l-arginine to l-ornithine and urea; a key enzyme of the urea cycle.

arginase

an enzyme of the urea cycle in the liver that splits arginine into urea and ornithine; abbreviated ARG. Significant amounts occur only in ureotelic mammals such as dogs, cats, sheep, pigs, rats and humans. Elevated blood levels are associated with acute hepatic necrosis and determination of arginase levels in plasma or serum is a good liver-specific test in these species. Called also arginine amidinase, canavanase.
References in periodicals archive ?
She came to my house, met me and my family and we shared my story with arginase seficiency.
Arginase inhibitory activity of several natural polyphenols using a novel in vitro test on purified arginase.
Given that arginase 1 reactivity was not observed in Iba1-positive cells of either genotype, this suggests that activated microglia temporarily appeared during development but did not show the typical arginase 1-positive M2 phenotype.
Blocking arginase using the small drug difluoromethylornithine (DFMO) before the start of symptoms in the mice, the scientists saw fewer CD11c microglia and plaques develop in their brains.
Contribution of arginase activation to vascular dysfunction in cigarette smoking.
Elevated Arginase and Limited Arginine Availability: a Common Feature in Asthma and Sickle Cell Disease.
Additional contributors to NO depletion in the diabetic kidney are NOS uncoupling, reduced membranal eNOS activity, and increased levels of PKC, ADMA, and intracellular arginase with consequent L-arginine depletion [17, 32].
3) With the exception of Arginase deficiency, all other enzyme deficiencies of the UCD result in low plasma concentration of arginine, and thus, the arginine availability may become a rate limiting step in the NO generation.
A confounding variable that has recently been postulated to contribute to the disparate results seen with L-arginine cardioplegia is the presence and activity of the enzyme arginase within the myocardium.
pylori also evade immune system by producing enzyme arginase which prevents nitric oxide (NO) production and therefore, it can survive within macrophages by interfering with lysosomal proteins.