arginase


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Related to arginase: Argininosuccinate

arginase

 [ahr´jĭ-nās]
an enzyme of the liver that splits arginine into urea and ornithine.

ar·gi·nase

(ar'ji-nās),
An enzyme of the liver that catalyzes the hydrolysis of l-arginine to l-ornithine and urea; a key enzyme of the urea cycle. A deficiency of arginase leads to arginemia.
Synonym(s): canavanase

arginase

/ar·gi·nase/ (ahr´jĭ-nās) an enzyme existing primarily in the liver, which hydrolyzes arginine to form urea and ornithine in the urea cycle.

arginase

(är′jə-nās′, -nāz)
n.
An enzyme found primarily in the liver that catalyzes the hydrolysis of arginine to form urea and ornithine.

arginase

[är′jinās]
an enzyme that catalyzes the hydrolysis of arginine during the urea cycle, producing urea and ornithine. The enzyme is found primarily in the liver but also occurs in the mammary gland, testes, and kidney.

ar·gi·nase

(ahr'ji-nās)
An enzyme of the liver that catalyzes the hydrolysis of l-arginine to l-ornithine and urea; a key enzyme of the urea cycle.

arginase

an enzyme of the urea cycle in the liver that splits arginine into urea and ornithine; abbreviated ARG. Significant amounts occur only in ureotelic mammals such as dogs, cats, sheep, pigs, rats and humans. Elevated blood levels are associated with acute hepatic necrosis and determination of arginase levels in plasma or serum is a good liver-specific test in these species. Called also arginine amidinase, canavanase.
References in periodicals archive ?
ARG: Arginase Cytosol 1:950,000 AR (hyperargininemia) 7.
Blocking arginase using the small drug difluoromethylornithine (DFMO) before the start of symptoms in the mice, the scientists saw fewer CD11c microglia and plaques develop in their brains.
Ash's (2004) revision discusses a reciprocal inhibitory mechanism between arginase I and iNOS in mammals that prevents the production of overly high levels of NO.
13) The bulk of arg is normally metabolized by arginases, leading to ornithine and its downstream products (principally the polyamines).
Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells.
The study supports new therapeutic strategies aimed at increasing arginine levels either through nutritional supplements or by developing new drug therapies that disable the arginase enzyme that consumes arginine.
Altered Pancreatic Arginase Activity and a-Amylase Levels in Patients with Type 2 Diabetes and Alcoholic Pancreatitis, Advances in Environmental Biology, 3(2): 113-119.
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Elevated Arginase and Limited Arginine Availability: a Common Feature in Asthma and Sickle Cell Disease.
A key scientific target is the realisation of intelligent electronic devices which respond to biomolecules such as formaldehyde, amines, metal ions, saccharides, activities of amine oxidases, arginase and glutathione-S-transferase.
2]-Macroglobulin IPI00478003 639 Annexin A1 IPI00218918 297 Annexin A2 IPI00455315 116 Annexin A3 IPI00024095 85 Annexin A5 IPI00329801 268 Antithrombin III IPI00032179 18 Apolipoprotein A-I IPI00021841 593 Apolipoprotein E IPI00021842 51 Arginase 1 IPI00038356 43 [[beta].
A confounding variable that has recently been postulated to contribute to the disparate results seen with L-arginine cardioplegia is the presence and activity of the enzyme arginase within the myocardium.