argentaffinoma


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argentaffinoma

 [ahr″jen-taf″ĭ-no´mah]
a carcinoid tumor of the gastrointestinal tract formed from argentaffin cells, usually in the terminal ileum or appendix; such tumors elaborate a variety of catecholamines that produce the symptom complex called carcinoid syndrome. Called also carcinoid.

argentaffinoma

/ar·gen·taf·fi·no·ma/ (ahr″jen-taf″ĭ-no´mah) a carcinoid tumor of the gastrointestinal tract formed from the argentaffin cells of the enteric canal and producing carcinoid syndrome.

argentaffinoma

pl. argentaffinomas, argentaffinomata, [är′jentaf′inō′mə]
a tumor that secretes large amounts of the hormone serotonin. It usually arises in the GI tract anywhere between the stomach and rectum and can metastasize to the liver. In the liver the tumor produces and releases large quantities of serotonin into the systemic bloodstream, resulting in carcinoid syndrome, which is characterized by flushing, swelling of the face, flat angioma on the skin, diarrhea, bronchial spasm, rapid pulse, low blood pressure, and tricuspid and pulmonary stenosis, often with regurgitation. Treatment is with surgery, radiation therapy, chemotherapy, or biotherapy. Carcinoid tumors are considered a type of endocrine tumor.

argentaffinoma

(1) Carcinoid tumour. 
(2) An obsolete, nonspecific term for any tumour with staining affinity for silver salts—e.g., carcinoids, APUDomas and pancreatic islet cell tumours; most argentaffinomas are neuroendocrine cell tumours.

argentaffinoma

Oncology A tumor located anywhere in the GI tract–± 90% in appendix, remainder are in the ileum, stomach, colon or rectum or lungs, which secretes excess serotonin, evoking a carcinoid syndrome. See APUD system, Carcinoid syndrome.

car·ci·noid tu·mor

(kahr'si-noyd tū'mŏr)
A neoplasm composed of cells of medium size, with moderately small vesicular nuclei; neoplastic cells are frequently palisaded at the periphery of small groups. Such neoplasms occur in the gastrointestinal tract, the lungs, and other sites, with approximately 90% in the appendix.
See also: carcinoid syndrome
Synonym(s): argentaffinoma.

argentaffinoma

a tumor arising from argentaffin cells, most frequently in the duodenum, colon and rectum of dogs. Called also carcinoid. Such tumors produce carcinoid syndrome.