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arformoterol

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arformoterol,
a long-acting adrenergic beta2-agonist, sympathomimetic, and bronchodilator.
indications This drug is used to treat chronic obstructive pulmonary disease, including chronic bronchitis and emphysema.
contraindications Tachydysrhythmias, severe cardiac disease, heart block, actively deteriorating chronic obstructive pulmonary disease, and known hypersensitivity to this drug, sympathomimetics, or racemic formoterol prohibit its use.
adverse effects Adverse effects of this drug include insomnia, headache, dizziness, stimulation, hallucinations, flushing, irritability, palpitations, tachycardia, hypertension, angina, hypotension, dysrhythmias, dry nose, irritation of nose and throat, heartburn, nausea, vomiting, flushing, sweating, anorexia, bad taste/smell changes, hypokalemia, muscle cramps, cough, wheezing, dyspnea, and dry throat. Life-threatening side effects include anaphylaxis and bronchospasm. Common side effects include tremors, anxiety, and restlessness.


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Currently marketed products include LUNESTA([R]) brand eszopiclone, XOPENEX([R]) brand levalbuterol HCl Inhalation Solution, XOPENEX HFA([R]) brand levalbuterol tartrate Inhalation Aerosol, BROVANA([R]) brand arformoterol tartrate Inhalation Solution, OMNARIS[TM] brand ciclesonide Nasal Spray and ALVESCO([R]) brand ciclesonide HFA Inhalation Aerosol.
Arformoterol - Sepracor has completed more than 100 preclinical studies and 16 clinical studies for arformoterol inhalation solution as a maintenance treatment for COPD.
During his six years with Sepracor he led clinical development activities for the asthma drug Levalbuterol and the COPD drug Arformoterol, through FDA approvals in 2005 and 2006 respectively.
 
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