arecoline


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a·rec·o·line

(ă-rek'ō-lēn),
A colorless oily alkaloid derived from the betel nut; a cholinomimetic.

arecoline

(ă-rek′ŏ-lēn″) [ areca + -ol + -ine]
An alkaloid found in the betel nut that causes cholinergic toxicity when the nut is chewed. Arecoline also causes periodontal disease and cancer of the upper gastrointestinal tract.

arecoline

an alkaloid obtained from the nut of the tree Areca catechu. Previously, a preferred treatment for cestodes in dogs. The acetarsol, hydrobromide and carboxyphenylstilbonate salts have been used for this purpose. Oral administration causes paralysis of the worms and catharsis, so the worms are expelled alive and intact. Lower doses are used as a laxative.

arecoline challenge test
used in the diagnosis of narcolepsy in dogs; pretreatment with atropine reduces the number of cataleptic attacks with exposure to food.
References in periodicals archive ?
they increase the genetic susceptibility of OSMF patients resulting in more penetration of arecoline and arecaidine into the oral mucosa.
Whether arecoline is present in leaves and stems of the plant is currently under investigation.
Membrane permeability studies have been proven that arecoline and arecaidaine diffuses across a stratified epithelium.
Clinical pharmacokinetics of arecoline in subjects with Alzheimer's disease.
This was followed by studies of muscarinic agonists, such as bethanechol, arecoline and oxotremorine, but adverse effects and low selectivity for the central nervous system limited their clinical use [15].
31] Based on biochemical studies of areca nut, four alkaloids have been conclusively identified: arecoline, arecaidine, guvacine and guvacoline, among which arecoline is the main agent.
The inflammatory process in buccal mucosa is exacerbated by a compound called Arecoline which is the main component of Areca nut.
5) Alkaloids present in the areca nut, assessed biochemically include arecoline, arecaidine, guvacine and guvacoline, of which arecoline is the main agent (Flowchart 1).
Such chemicals include hydroxychavicol, chavibetol, piperbetol, arecoline, carvacrol, caryophyllene, piperitol, eugenol, isoeugenol, allyl pyrocatechol, chavicol, safrole, anethole, betasitosterol, beta-sitosteryl palmitate, dotriacontanoic acid, tritriacontane, piperine, piperlonguminine, chavibetol acetate, estragole, piperols A and B, and pyrocatechol diacetate (Zeng et al.
Diagnosis of canine echinococcosis: comparison of coproanigen and serum antibody tests with arecoline purgation in Uruguay.
However, hypoglycemic activity has also been reported for arecoline (Chempakam, 1993).
The present study analyses the effect of eugenol, arecoline and vanillic acid alone and in combination with two oral hypoglycemic drugs (OHD), namely, metformin and 2,4-thiazolodinedione (THZ), on 2-deoxyglucose (2DG) uptake in L6 myotubes.