arachidonate


Also found in: Dictionary, Encyclopedia.
Related to arachidonate: Phosphatidate

arachidonate

A salt, ester or anion of arachidonic acid, see there.

arachidonate

A salt, ester, or anion of arachidonic acid
References in periodicals archive ?
Ethyl arachidonate in both liver and adipose tissue was markedly higher in individuals with detectable blood ethanol at the time of autopsy than in chronic alcoholics and social drinkers.
2,4,5) However, the spectrum of eicosanoids and expression of arachidonate pathway enzymes has not been characterized in OA cartilage.
Human MPM cells, but not normal mesothelial cells, express a catalytically active arachidonate 5-lipoxygenase (5-LO).
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
Daphnetin (7,8-dihydroxy-coumarin) has been recognised as an inhibitor of the proinflammatory lipoxygenase and cyclooxygenase pathways of arachidonate metabolism with strong inhibition of lipid peroxidation and glutathione reductase activity (Fylaktakidou et al.
Intact platelets do not accumulate arachidonate following DHLA administration, and species differences occur in the capacity of animals to metabolize DHLA to arachidonic acid (AA).
RESULTS: After accounting for multiple testing and comparing homozygotes, tagSNPs in the type 1 angiotensin II receptor (AGTR1, rs6801836) and arachidonate 15-lipoxygenase (ALOX15, rs2664593) genes were each significantly (q < 0.
Blood-vessel wall arachidonate metabolism and its pharmacological modification in a new in vitro assay system.
The initial phase of carrageenan paw edema is mediated by histamine and serotonin, while the mediators in the later phase were suggested to be arachidonate metabolites (prostaglandins and leukotrienes) producing an edema dependent on the mobilization of neutrophils (Vinegar et at.
In addition, ionising radiation enhances lysosomal enzyme secretion and arachidonate release from membranes through lipo-oxygenase, cyclo-oxygenase and phospholipase activities, thus increasing the inflammatory cell response.
These include enzymes for prostaglandin synthesis, such as prostaglandin D2 synthase and prostaglandin-endoperoxide synthase 2 (cyclooxigenase 2, COX2) and enzymes for leukotriene synthesis, such as arachidonate 12-lipoxygenase and arachidonate 15-lipoxygenase.