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apurinic-apyrimidinic (AP) endonuclease |
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apurinic-apyrimidinic (AP) endonuclease enzyme involved in the excision repair mechanism of DNA. The enzyme nicks the phosphodiester backbone at the depurinized site and excises the sugar phosphate residue, prior to restoration of the damaged strand by the action of DNA polymerase I and ligase. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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