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apoptosis

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
apoptosis /ap·op·to·sis/ (ap?op-to´sis) a pattern of cell death affecting single cells, marked by shrinkage of the cell, condensation of chromatin, and fragmentation of the cell into membrane-bound bodies that are eliminated by phagocytosis. Often used synonymously with programmed cell death. apoptot´ic
ap·op·to·sis (pp-tss, p-t-)
n.
A natural process of self-destruction in certain cells that is determined by the genes and can be initiated by a stimulus or by removal of a repressor agent. Also called programmed cell death.

apoptosis (a·pp·tōˑ·sis),
n programmed destruction of cells; mechanism that keeps cell numbers in check by eliminating senescent cells or those without useful cell function.

apoptosis (ap´tō´sis),
n cell reduction by fragmentation into membrane-bound particles that are phagocytosed by other cells.

apoptosis
programmed cell death, a process including coagulative necrosis and shrinkage.

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Lymphocytes, in particular, undergo massive and apparently unregulated apoptosis in human patients and laboratory animals with sepsis, potentially playing a major role in the severe immunosuppression that characterizes the terminal phase of fatal illness.
Studies have shown that inhibition or depletion of RLIP76, a glutathione-conjugate transport protein that helps cells defend themselves against toxicants, causes apoptosis in a number of cancer cell types.
By reawakening the apoptosis that seems to fail in many tumor cells, J.
 
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