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apomorphine |
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apomorphine, an antiparkinson agent. indications This drug is used for acute, intermittent treatment of hypomobility episodes in advanced parkinsonism. contraindications Known hypersensitivity to this drug prohibits its use. adverse effects Adverse effects of this drug include psychosis, hallucination, depression, dizziness, headache, confusion, yawning, dyskinesias, drowsiness, somnolence, edema, syncope, tachycardia, blurred vision, rhinorrhea, sweating, vomiting, constipation, dysphagia, dry mouth, impotence, and urinary frequency. Life-threatening side effects include sleep attacks, hemolytic anemia, leukopenia, and agranulocytosis. Common side effects include agitation, orthostatic hypotension, nausea, and anorexia. apomorphine an alkaloid from morphine. Used as the hydrochloride; administered parenterally it causes vomiting within 3 to 10 minutes but can also be administered orally. Stimulates receptors in the chemoreceptor trigger zone of the medulla oblongata. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Tokyo, Japan, Feb 23, 2006 - (JCN) - Kyowa Hakko Kogyo announced on February 22 that it has concluded a licensing agreement with UK company Britannia Pharmaceuticals for a self-injectable formulation of apomorphine. Patients were randomized to commence either sildenafil or apomorphine treatment. These investigators administered two proteasomal inhibitors (epoxomicin and PSI) to rats over a 14-day period and then observed a progressive deterioration in motor function over a 2-week period, which improved after administration of the dopamine agonist apomorphine. |
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