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apomorphine

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
ap·o·mor·phine (p-môrfn)
n.
A poisonous, white, crystalline alkaloid derived from morphine and used medicinally to induce vomiting.

apomorphine,
an antiparkinson agent.
indications This drug is used for acute, intermittent treatment of hypomobility episodes in advanced parkinsonism.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include psychosis, hallucination, depression, dizziness, headache, confusion, yawning, dyskinesias, drowsiness, somnolence, edema, syncope, tachycardia, blurred vision, rhinorrhea, sweating, vomiting, constipation, dysphagia, dry mouth, impotence, and urinary frequency. Life-threatening side effects include sleep attacks, hemolytic anemia, leukopenia, and agranulocytosis. Common side effects include agitation, orthostatic hypotension, nausea, and anorexia.

apomorphine
an alkaloid from morphine. Used as the hydrochloride; administered parenterally it causes vomiting within 3 to 10 minutes but can also be administered orally. Stimulates receptors in the chemoreceptor trigger zone of the medulla oblongata.


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Others Apomorphine (Uprima), phentolamine (Vasomax), vasodilators (nitroglycerine), pentoxifylline (Trental), trazodone (Desyrel) and others have been tried alone and in combinations, with limited success.
Its goal was to use brain scans to study what happens when people take apomorphine, which is a drug for Parkinson's disease, a condition marked by alack of dopamine.
Oral administration with DA-9701 not only significantly accelerated gastric emptying in normal rats but also restored the delayed gastric emptying caused by apomorphine and cisplatin up to almost normal levels.
 
 
 
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