apomorphine


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Related to apomorphine: Apomorphine hydrochloride

apomorphine

(ăp′ə-môr′fēn′)
n.
A poisonous alkaloid, C17H17NO2, that is an analog of morphine and is used medicinally to treat Parkinson's disease and to induce vomiting.

apomorphine

an antiparkinson agent.
indications This drug is used for acute, intermittent treatment of hypomobility episodes in advanced parkinsonism.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include psychosis, hallucination, depression, dizziness, headache, confusion, yawning, dyskinesias, drowsiness, somnolence, edema, syncope, tachycardia, blurred vision, rhinorrhea, sweating, vomiting, constipation, dysphagia, dry mouth, impotence, and urinary frequency. Life-threatening side effects include sleep attacks, hemolytic anemia, leukopenia, and agranulocytosis. Common side effects include agitation, orthostatic hypotension, nausea, and anorexia.

apomorphine

A morphine derivative used as an expectorant, emetic, and hypnotic. In large doses it promotes severe vomiting. Used in the treatment of Parkinson's disease. Brand names are Apo-go and Uprima.

apomorphine

an alkaloid from morphine. Used as the hydrochloride; administered parenterally it causes vomiting within 3 to 10 minutes but can also be administered orally. Stimulates receptors in the chemoreceptor trigger zone of the medulla oblongata.
References in periodicals archive ?
Research conducted suggests that the current use of apomorphine as a rescue therapy to treat "off" episodes is limited by the current form of delivery, and that a more user-friendly oral form would lead to greater level of prescriptions and use by patients.
While currently available and approved oral erectogenic therapeutic agents include only sildenafil, and possibly apomorphine, the mechanisms of action currently manipulated by these agents are limited.
oral phentolamine, apomorphine, topical agents), physicians will need a better functional classification for the medical treatment of ED.
In each group, 45 patients were taking apomorphine at study entry; 145 total were taking it before the study.
s apomorphine ``works completely in the brain,'' Padma-Nathan said.
The AOK Bavaria intends to enter into force one by nation-wide or country-specific, closed the open procedure Off Treaty on drugs containing apomorphine - close ATC N04BC07, with all interested pharmaceutical companies, non-exclusive discount agreements pursuant to ?
For example, the well known plant alkaloids include the narcotic analgesics, morphine and codeine, apomorphine (a derivative of morphine) used in Parkinson's disease, the muscle relaxant papaverine, and the antimicrobial agents sanguinarine and berberine.
Clinicians are left with ropinirole, and pramipexole, and, as a rescue medicine, subcutaneous apomorphine, said Dr.
SAN FRANCISCO -- A single dose of subcutaneous apomorphine rapidly and effectively reverses for at least 90 minutes the hypomobility, or "off," episodes that are common in patients with advanced Parkinson's disease, William C.
In trials it was used to administer apomorphine, a drug that tackles erectile dysfunction which affects one in 10 men.
The women, who suffer from lack of sexual desire, were treated with a drug called apomorphine.