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apomorphine

   Also found in: Dictionary/thesaurus, Wikipedia, Hutchinson 0.05 sec.
ap·o·mor·phine (p-môrfn)
n.
A poisonous, white, crystalline alkaloid derived from morphine and used medicinally to induce vomiting.

apomorphine
an alkaloid from morphine. Used as the hydrochloride; administered parenterally it causes vomiting within 3 to 10 minutes but can also be administered orally. Stimulates receptors in the chemoreceptor trigger zone of the medulla oblongata.


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Tokyo, Japan, Feb 23, 2006 - (JCN) - Kyowa Hakko Kogyo announced on February 22 that it has concluded a licensing agreement with UK company Britannia Pharmaceuticals for a self-injectable formulation of apomorphine.
Patients were randomized to commence either sildenafil or apomorphine treatment.
These investigators administered two proteasomal inhibitors (epoxomicin and PSI) to rats over a 14-day period and then observed a progressive deterioration in motor function over a 2-week period, which improved after administration of the dopamine agonist apomorphine.
 
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