apolipoprotein B100

apolipoprotein B100

A protein encoded by APOB on chromosome 2p24-p23, a major chylomicron component synthesised in the intestine that is essential for intestinal absorption of dietary fats and fat-soluble vitamins.
References in periodicals archive ?
12) Furthermore, the VAP test provides measurements of various lipid components including HDL, TC (VLDL), non-HDL, apolipoprotein B100 (apoB100), Lp(a), IDL, LDL-R, LDL-R subclasses, and remnant lipoproteins such as VLDL3.
At the end of 12 weeks, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C), and apolipoprotein B100 (Apo B100) were significantly lower in the soy nut group compared with the control group.
Association of high-density lipoprotein cholesterol with incident cardiovascular events in women, by low-density lipoprotein cholesterol and apolipoprotein B100 Levels: a cohort study.
562] In Vivo Comparison of the Long-Term Efficacy of AAV Expressed ShRNA and MiRNA Targeting Apolipoprotein B100 Authors: Piotr Maczuga, Annemart Koornneef, Richard van Logtenstein, Florie Borel, Harald Petry, Sander van Deventer, Pavlina Konstantinova Date/Time: Friday, May 20, 2011 - 4:40 pm
Birmingham, AL), developer of the VAP Cholesterol Test, announced it has received a patent on its method to derive and report apolipoprotein B100 (apoB) using the Vertical Auto Profile (VAP) technology.
Apolipoprotein B100 (apoB) is the structural protein of the atherogenic lipoproteins.
Is vitellogenin an ancestor of apolipoprotein B100 of human low-density lipoprotein and human lipoprotein lipase?
Cholesterol Testing II-12 Need for Cholesterol Testing II-12 Candidates for Cholesterol Testing II-12 Test Procedure II-13 Time of Testing - Crucial for Heart Disease Patients II-13 Types of Cholesterol Testing II-14 Lipid Panel Test/Lipid Profile II-14 Total Cholesterol Test II-14 HDL Cholesterol Test II-14 Apolipoprotein Tests II-15 Apolipoprotein A-1 Test II-15 Apolipoprotein B100 Test II-15 ApoE Genotyping Test II-15 Apolipoprotein CII II-16
Euronext: AMT), a leader in the development of gene based therapies, today announced that its gene therapy product incorporating siRNA sequences into microRNA scaffolds to silence Apolipoprotein B100 (AAV-miApoB) was able to significantly lower plasma cholesterol levels in vivo over a period of 18 weeks.
Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9.
The data show that a single dose of the gene therapy carrying a short hairpin RNA to silence Apolipoprotein B100 (ApoB100), resulted in a reduction of serum cholesterol of approximately 80%, without any signs of toxicity.
The key to understanding these particles relates to the metabolism of the apolipoprotein B100 (Apo B)-containing particles secreted by the liver.