apolipoprotein B-48

ap·o·lip·o·pro·tein B-48

an apolipoprotein found in chylomicrons and chylomicron remnants. Retained in the intestines of patients with chylomicron retention disease.

apolipoprotein B-48

A 250 kD protein that is a major chylomicron component synthesized in the intestine; ApoB-48 has an obligatory role in the synthesis of chylomicrons and is essential for intestinal absorption of dietary fats and fat-soluble vitamins
References in periodicals archive ?
Fasting and postprandial apolipoprotein B-48 levels in healthy, obese, and hyperlipidemic subjects.
Objective: This study aimed to investigate effects of chronic black tea consumption on concentrations of chylomicrons and chylomicron remnants using plasma concentrations of apolipoprotein B-48 as a marker.
Main outcome measures: Plasma apolipoprotein B-48, lathosterol, and serum lipid measurements were taken from fasting blood samples at the end of each four-week period.
Statistical analysis: Paired t-tests were used to compare concentrations of apolipoprotein B-48, lathosterol and serum lipids after tea consumption with those after hot water control.
Results: Comparing ingestion of black tea to hot water, we found no changes in apolipoprotein B-48, lathosterol or serum lipids collectively.
Effects of intensive atorvastatin and rosuvastatin treatment on apolipoprotein B-48 and remnant lipoprotein cholesterol levels.
Triglyceride-rich RLPs are formed in the circulation when chylomicrons of intestinal origin [with apolipoprotein B-48 (apo B-48)] and VLDL of hepatic origin (with apo B-100) are converted by lipoprotein lipase (and to a lesser extent by hepatic lipase) into smaller and more dense particles.
Postprandial chylomicron response may be predicted by a single measurement of plasma apolipoprotein B-48 in the fasting state.
Apolipoprotein B-48 (apoB-48) [4] is an excellent marker of postprandial lipoproteins because it is associated exclusively in humans with intestinally derived chylomicrons (CMs) and their remnants, circulating particles that have been described as atherogenic (1).
A novel antiserum specific to apolipoprotein B-48 application in the investigation of postprandial lipidaemia in humans.
Quantification of apolipoprotein B-48 in triacylglycerol-rich lipoproteins specific enzyme-linked immunosorbent assay.
Apolipoprotein B-48 and retinyl-palmitate are not equivalent markers of post prandial intestinal lipoproteins.