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apolipoprotein B-100

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apolipoprotein B-100,
a protein component of lipoprotein involved in the hepatic transport of lipid as very-low-density lipoprotein and low-density lipoprotein (LDL). Apoprotein B-100 links to cellulose LDL receptors. It is elevated in the plasma of patients with familial hyperlipoproteinemia.

apolipoprotein B-100
A 550 kD protein synthesized in the liver that is the major component in lipoproteins of endogenous origin–LDL, VLDL, IDL, provides the recognition signal targeting LDL to the LDL–apoB, E receptor and is considered to be the l'enfant terrible of ASHD Ref range 40 to 125 mg/dl Abnormal values ↑ in familial combined hyperlipidemia, acquired hyperlipidemia, in acute angina and MI


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