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apolipoprotein A-I |
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apolipoprotein A-I, a protein component of lipoprotein complexes found in high-density lipoprotein (HDL) and chylomicrons. It is an activator of lecithin-cholesterol acyltransferase, which forms cholesteryl esters in HDL. All apoproteins of plasma lipoproteins bind and transport lipid in the blood. A deficiency of apolipoprotein A-I is associated with low HDL levels and Tangier disease. apolipoprotein A-I A 28 kD single chain protein that comprises 75% of the ApoA in HDL; apoA-I is the major protein constituent of lipoproteins, and participates in cholesterol transport by activating LCAT-lecithin:cholesterol acyltransferase;
apoA-I levels are inversely proportional to the risk of CAD How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Other scientists had shown that excess apolipoprotein A-I reduces the risk of atherosclerosis in mice. Metabolic Effects of Intravenous Infusion of Apolipoprotein A-I / Phosphatidylcholine (apo a-I/PC) Discs in Humans |
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