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apolipoprotein A-I

   Also found in: Wikipedia 0.01 sec.
apolipoprotein A-I,
a protein component of lipoprotein complexes found in high-density lipoprotein (HDL) and chylomicrons. It is an activator of lecithin-cholesterol acyltransferase, which forms cholesteryl esters in HDL. All apoproteins of plasma lipoproteins bind and transport lipid in the blood. A deficiency of apolipoprotein A-I is associated with low HDL levels and Tangier disease.

apolipoprotein A-I
A 28 kD single chain protein that comprises 75% of the ApoA in HDL; apoA-I is the major protein constituent of lipoproteins, and participates in cholesterol transport by activating LCAT-lecithin:cholesterol acyltransferase; apoA-I levels are inversely proportional to the risk of CAD


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In lab experiments with mice, Chinese researchers found abnormal forms of a protein, apolipoprotein A-I (Apo A-I), in the livers of infected male mice but not infected females.
College of American Pathologists'in (CAP) eksternal kalite kontrol verilerine gore, programlari na dahil Amerika'daki tum laboratuvarlar apolipoprotein A-I ve apolipoprotein B'yi immunoturbidimetrik veya immunonefelometrik metotlarindan biriyle olcmektedirler.
Apolipoprotein A-I is the major protein moiety of HDL, determines the plasma concentration of HDL, and protects against atherogenesis.
 
 
 
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