apo A-IV

apo A-IV

A gene that encodes apo A-IV; allelic polymorphism in apo A-IV results in the substitution of histidine for glutamine at position 360 near the COOH terminus, generating the isoform apo IV-2, which attenutates the hypercholesterolemic response to dietary cholesterol. See Apolipoprotein A-IV.
References in periodicals archive ?
The are labeled Apo A-I, Apo A-II, Apo A-IV, Apo B-100, Apo B-48, Apo C-1, Apo C-II, Apo C-III, Apo E and Apo(a).
Within the plasma compartment, apo A-IV dissociates from chylomicrons (4) and associates with HDL, triglyceride-rich lipoproteins, and the lipoprotein-free fraction (5).
Apo A-IV is influenced by dietary intervention, and a low-fat, low-cholesterol diet (NCEP Step II diet) and is able to decrease apo A-IV secretion rates significantly (6).
Other apolipoprotein species found in HDL particles include apo A-II, apo A-IV, apo CI, apo CIII, and apo E.
Some PL might be bound to another apo, such as apo A-IV, of which there is a minor peak in this region (Nanjee and Brinton, unpublished results), but such particles also are likely to contain little PL.