aphthous stomatitis


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stomatitis

 [sto″mah-ti´tis] (pl. stomati´tides)
inflammation of the mucosa of the mouth; it may be caused by any of numerous diseases of the mouth or it may accompany another disease. Both gingivitis and glossitis are forms of stomatitis.

Causes. The causes of stomatitis vary widely, from a mild local irritant to a vitamin deficiency or infection by a possibly dangerous disease-producing organism. Inflammation may arise from actual injury to the inside of the mouth, as from cheek-biting, jagged teeth, tartar accumulations, and badly fitting dentures. Irritating substances, including alcohol, and tobacco, may also cause stomatitis. Other causes are infectious bacteria, such as streptococci and gonococci or those causing necrotizing ulcerative stomatitis, diphtheria, and tuberculosis; the fungus causing thrush; or the viruses causing herpes simplex and measles. Extreme vitamin deficiencies can result in mouth inflammation, as can certain blood disorders. Poisoning with heavy metals, such as lead or mercury, can also cause stomatitis.
Symptoms. There is generally swelling and redness of the tissues of the mouth, which may become quite sore, particularly during eating. The mouth may have an unpleasant odor. In some types of stomatitis the mouth becomes dry, but in others there is excessive salivation. Ulcerations may appear, and, in extreme cases, gangrene (gangrenous stomatitis).

Other forms of stomatitis may occasionally cause more severe symptoms, including chills, fever, and headache. Sometimes bleeding or white patches in the mouth can be seen. In thrush, the symptoms themselves may be slight (white spots in the mouth resembling milk curds) but the disease may give rise to serious infections elsewhere in the body. In some cases, stomatitis causes inflammation of the parotid glands.

Stomatitis resulting from certain diseases presents special identifying symptoms. Syphilitic stomatitis produces painful ulcers in the mouth; in scarlet fever the tongue first has a strawberry color, which then deepens to a raspberry hue; in measles, Koplik's spots appear.
Treatment and Prevention. The treatment varies according to the cause. When the inflammation is caused by anemia, vitamin deficiency, or any infection of the body, both the underlying disease and the stomatitis are treated. Antibiotics often are effective against the infection and prevent its spreading to the parotid glands. Severe stomatitis can be a side effect of chemotherapy and radiation to the head and neck as treatment for cancer. Measures to alleviate the inflammation and promote healing include increasing fluid intake and using artificial saliva to minimize dryness and help buffer acidity in the mouth, avoiding liquids and foods that are chemically irritating or extremely hot, and frequent and consistent mouth care.



With proper care, many cases of stomatitis can be prevented. Cleanliness is essential, especially of the mouth, teeth, dentures, and feeding utensils. Infants may acquire mouth infection from the mother's oral flora, dirty bottles, or the mother's nipples. In the case of a prolonged fever or of any severe general illness, dryness of the mouth should be avoided by ingestion of increased amounts of fluids.
angular stomatitis superficial erosions and fissuring at the angles of the mouth; it may occur in riboflavin deficiency and in pellagra or result from overclosure of the jaws in denture wearers. Called also perlèche.
aphthous stomatitis recurrent aphthous stomatitis.
denture stomatitis inflammation of the oral mucosa seen in some patients with new dentures or with old, ill-fitting ones, caused by Candida albicans; characterized by redness, swelling, and pain of mucosa that is in contact with the denture. Called also chronic atrophic candidiasis and denture sore mouth.
gangrenous stomatitis see noma.
herpetic stomatitis herpes simplex involving the oral mucosa and lips, characterized by the formation of yellowish vesicles that rupture and produce ragged painful ulcers covered by a gray membrane and surrounded by an erythematous halo.
stomatitis medicamento´sa stomatitis due to an allergic reaction to drugs ingested, absorbed through the skin or mucosa, or given by hypodermic injection. Principal symptoms include vesicles, erosion, ulcers, erythema, purpura, angioedema, burning, and itching.
recurrent aphthous stomatitis a recurrent disease of unknown etiology, characterized by one or more small round or oval ulcer(s) on the oral mucosa, covered by a grayish fibrinous exudate and surrounded by a bright red halo. The lesions usually persist for 7 to 14 days and then heal without scarring. Called also aphthae, aphthous stomatitis, and canker sore.

aph·tha

, pl.

aph·thae

(af'thă, af'thē), Avoid the misspelling/mispronunciation aptha.
1. In the singular, a small ulcer on a mucous membrane.
2. In the plural, stomatitis characterized by intermittent episodes of painful oral ulcers of unknown etiology that are covered by gray exudate, are surrounded by an erythematous halo, and range from several millimeters to 2 cm in diameter; they are limited to oral mucous membranes that are not bound to periosteum, occur as solitary or multiple lesions, and heal spontaneously in 1-2 weeks. Synonym(s): aphthae minor, aphthous stomatitis, canker sores, recurrent aphthous stomatitis, recurrent aphthous ulcers, recurrent ulcerative stomatitis, ulcerative stomatitis
[G. ulceration]

aphthous stomatitis

[af′thəs]
Etymology: Gk, aphtha, eruption; stoma, mouth, itis, inflammation
a recurring condition characterized by the eruption of painful ulcers (commonly called canker sores) on the mucous membranes of the mouth. Evidence suggests that the condition is an immune response. Heredity, some foods, emotional stress, cancer, and fever are also possible causes.
enlarge picture
Aphthous stomatitis

aph·tha

, pl. aphthae (af'thă, -thē)
1. In the singular, a small ulcer on a mucous membrane.
2. In the plural, stomatitis characterized by episodes of painful oral ulcers of unknown etiology that are covered by gray exudate, are surrounded by an erythematous halo, and that heal spontaneously in 1-2 weeks.
Synonym(s): aphthae minor, aphthous stomatitis, canker sores, recurrent aphthous ulcers, recurrent ulcerative stomatitis, ulcerative stomatitis.
[G. ulceration]

stomatitis

(sto-ma-tit'is) [ stomato- + -itis]
Enlarge picture
STOMATITIS: As caused by herpes simplex virus
Inflammation of the mouth (including the lips, tongue, and mucous membranes). See: illustration; noma; thrush

Etiology

Stomatitis may be associated with viral infections, chemical irritation, radiation therapy, mouth breathing, paralysis of nerves supplying the oral area, chemotherapy that damages or destroys the mucous membranes, adverse reactions to other medicines, or acute sun damage to the lips. The nasal and oral mucosa are esp. vulnerable to trauma from dental appliances, nasal cannula, nasotracheal tubes, or catheters administering nutrients. These areas may also be damaged during surgery when an endotracheal tube is in place.

Symptoms

Symptoms include oral pain, esp. when eating or drinking, bad breath, or difficulty in swallowing. Findings include oral ulcers, friability of the mucous membranes, swollen cervical lymph nodes, and sometimes fever.

Patient care

Treatment depends on the cause but is often symptomatic. The mucous membranes should be kept moist and clear of tenacious secretions. Care of the teeth and gingival tissues should be comprehensive and include flossing. The pain of stomatitis may be alleviated by systemic analgesics or application of anesthetic preparations to painful lesions. It is important for patients with dentures to clean their dentures thoroughly. Dentures should be removed from unconscious or stuporous patient. See: toothbrushing

aphthous stomatitis

Aphthous ulcer.

corrosive stomatitis

Stomatitis resulting from intentional or accidental exposure to corrosive substances.

denture stomatitis

Stomatitis on the oral mucosa covered by full or partial dentures, most commonly seen on the palate although the inflammation may also be seen overlying the mandible.

Patient care

Although most patients are asymptomatic (the finding is noticed by dental professionals during oral examination, rather than by the patient), the condition should be treated to prevent progression to more serious oral diseases. Removal of plaque from dentures (as by brushing them carefully), removal of dentures at night, and sanitizing dentures regularly (as with an overnight soak in a chlorhexidine solution) all prevent the condition from occurring. Antifungal medications are used if fungi are isolated on culture swabs.

Synonym: chronic atrophic candidiasis

diphtheritic stomatitis

Stomatitis caused by infection with Corynebacterium diphtheriae.
See: diphtheria

herpetic stomatitis

Stomatitis seen with primary infection with herpes simplex virus.

major aphthous stomatitis

Stomatitis in which large recurring or migrating painful ulcers appear within the oral cavity (on the gingiva and soft palate) and sometimes on the lips.

membranous stomatitis

Stomatitis accompanied by the formation of a false or adventitious membrane.

mercurial stomatitis

Stomatitiss seen in those exposed to elemental mercury or mercury vapors.

mycotic stomatitis

Thrush.

nicotine stomatitis

, stomatitis nicotina
Fissuring and the formation of hyperkeratotic papules on the palate, usually caused by habitual pipe smoking. It is a form of precancer.

simple stomatitis

Stomatitis occurring in patches on the mucous membranes.

traumatic stomatitis

Stomatitis resulting from mechanical injury as from ill-fitting dentures, sharp jagged teeth, or biting the cheek.

ulcerative stomatitis

Necrotizing ulcerative gingivitis.

vesicular stomatitis

Aphthous ulcer.

Vincent stomatitis

Necrotizing ulcerative gingivitis.

Aphthous stomatitis

A specific type of stomatitis presenting with shallow, painful ulcers. Also known as canker sores.
Mentioned in: Stomatitis

aphthous stomatitis (afˑ·thōs stōˈ·m·tīˑ·tis),

n a common condition that affects the oral cavity; indicated by the appearance of painful, shallow lesions found alone or in clustered groups. A reddish border surrounds the small ulcers, and a pseudo-membrane covers them. Injury to the mouth, sensitivity to certain foods, nutrient deficiency, and/or stress may cause it. The lesions typically heal within one to three weeks of appearance. Also called
common canker sore or
ulcerative stomatitis.
Enlarge picture
Aphthous stomatitis.

aph·tha

, pl. aphthae (af'thă, -thē) Avoid the misspelling/mispronunciation aptha.
1. In the singular, a small ulcer on a mucous membrane.
2. In the plural, stomatitis characterized by intermittent episodes of painful oral ulcers of unknown etiology that are covered by gray exudate, are surrounded by an erythematous halo, and range from several millimeters to 2 cm in diameter; they are limited to oral mucous membranes that are not bound to periosteum, occur as solitary or multiple lesions, and heal spontaneously in 1-2 weeks.
Synonym(s): aphthae minor, aphthous stomatitis, canker sores, recurrent aphthous stomatitis, recurrent aphthous ulcers, recurrent ulcerative stomatitis, ulcerative stomatitis.
[G. ulceration]

Patient discussion about aphthous stomatitis

Q. Is it possible to prevent appearance of oral aphthae? I get these a lot and lately I've heard it comes as a result of stress or weak immune system. Is that true? Is there a way to make it go away forever????? anyone who has ever had this annoying thing in his mouth knows what I'm talking about... I know all the possible curing ways- I'm looking for prevention now...thanx!

A. welcome to my life! every time the air get's a little dry i get 1-3 aphthae and can't eat for the next 4-6 days. so i investigated a little, and i'm sorry but right now no one really knows what causes them. they know that from some reason the body get's an immune reaction in the oral mucosa and that causes an ulcer. but a friend of mine went to an Ayurveda therapist that told him to stop eating tomatoes and eggplants (in any way, cooked,baked,fried) and he says he stop getting aphthae. so you might try Ayurveda for prevention. it could help...

Q. aphthous stomatitis can someone please explain me what it is? and what is the best way to treat it?

A. A canker sore (aphthous stomatitis) is an illness that causes small ulcers to appear in the mouth, usually inside the lips, on the cheeks, or on the tongue. What causes aphthous stomatitis (canker sores)?
The exact cause of this disease is not known. There are many factors that are thought to be involved with the development of canker sores, including:

Weakened immune system
Certain allergies may cause the lesions to appear, such as:
Coffee
Chocolate
Cheese
Nuts
Citrus fruits
Potatoes
Stress
Viruses and bacteria

The following are the most common symptoms of aphthous stomatitis. However, each child may experience symptoms differently. Symptoms may include:
Ulcers in the mouth, usually inside the lips, on the cheeks, or on the tongue
Ulcers that are covered with a yellow layer and have a red base
For the full article:
http://www.cincinnatichildrens.org/health/info/oral/diagnose/aphthous-stomatitis.htm Hope this helps.



More discussions about aphthous stomatitis
References in periodicals archive ?
Colchicine prophylaxis for frequent periodic fever, aphthous stomatitis, pharyngitis and adenitis episodes.
Periodic Fever, aphthous stomatitis, pharyngitis and adenopathy syndrome; clinical characteristics and outcome.
Periodic fever, aphthous stomatitis, phryngitis, and adenitis: a clinical review of a new syndrome.
Syndrome of periodic fever, aphthous stomatitis, phryngitis and adenitis (PFAPA): clinial review of a new syndrome.
Periodic fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis syndrome in adults.
Grade three and four adverse events (greater than or equal to 5%) with everolimus plus octreotide LAR were stomatitis (7%; includes stomatitis, aphthous stomatitis, mouth ulceration and tongue ulceration), fatigue (7%), diarrhea (6%), infections/infestations (5%) and hyperglycemia (5%)(9).
One recent study from Iran concluded that "a significant minority of recurrent aphthous stomatitis (RAS) patients have gluten-sensitive enteropathy.
Gluten sensitivity enteropathy in patients with recurrent aphthous stomatitis.
Since going public in 1996, the Company has focused on human clinical trials conducted in patients with fibromyalgia, aphthous stomatitis, Sjogren's syndrome, the common cold, hepatitis B, chronic fatigue syndrome and AIDS.
Digestive System: acid reflux, aphthous stomatitis, constipation, dental caries, dental pain, digestive gas symptoms, dry mouth, duodenal disorder, dysgeusia, esophagitis, flatulence, gastric disorder, gastritis, gastroenteritis, hematochezia, hemorrhoids, infectious gastroenteritis, oral infection, oral lesion, oral ulcer, vomiting.
Last June, the FDA granted the company orphan drug status for using thalidomide for treatment of recurrent aphthous stomatitis (mouth ulcers or canker sores) in severely, terminally immunocompromised patients suffering from such conditions as AIDS and cancer.
The differential diagnosis includes other causes of desquamative gingivitis and cicatricial conjunctivitis, which include pemphigus vulgaris, erythema multiforme, dermatitis herpetiformis, aphthous stomatitis, and Behcet's disease.