The authors state that achalasia "is an incurable disease characterized by incomplete or absent relaxation of the LES and aperistalsis
of the esophageal body.
On imaging and manometry, achalasia is further characterized by esophageal aperistalsis
and failure of the lower esophageal sphincter to relax.
Achalasia is an idiopathic motility disorder of the oesophagus characterised by aperistalsis
of the oesophageal body and incomplete relaxation of the lower oesophageal sphincter during swallowing (1).
Esophageal resection with reconstruction for peptic strictures is reserved for strictures that cannot be adequately dilated, rapid recurrence of a stricture after dilatation, or an irreversibly damaged esophagus with transmural fibrosis and evidence of aperistalsis
In one series, abnormal findings were present in 21% of patients and included thumbprinting, air-filled loops, colonic aperistalsis
, mural thickening, and exhausted bowel.
It was thought that less patient movement and duodenal aperistalsis
related to general anaesthesia may have made procedures technically easier and might have contributed to the low complication rate.
of the esophagus and colon etiologically related to Chagas' disease.
Physiologic changes in achalasia include failure of LES relaxation, esophageal aperistalsis
, and eventual esophageal dilation.