antiviral agent


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Related to antiviral agent: Antiviral drugs

antiviral agent

Antiviral Infectious disease An agent that prevents viral invasion or replication, treats an infection, or thrashes the virus into latency; antivirals may be specific–see below or nonspecific–eg, IFNs, which stimulate host defenses against viruses, making cells more resistant to viral genes, enhancing cellular immune responses or suppressing viral replication Types Inhibitors of viral DNA replication, transcription, or translation; topical surfactants; those that reduce viral infectivity by altering the lipid envelope; photodynamic inactivation with dyes which, when activated with UV light, are incorporated into the viral DNA, causing reading errors, IFN and IFN inducers, immune modulators and vaccines; AAs should not be used prophylactically, as their use selects for drug-resistant strains of virus.

antiviral agent

an agent that inhibits the REPLICATION of VIRUSES. Very few of these agents are suitable for clinical use, however, mainly because of toxic side effects and/or the occurrence of resistant strains.
References in periodicals archive ?
This study showed that SP-2a has remarkable antiviral activity against the ACV-resistant strain of HSV-1, and its potential for development as a novel antiviral agent against other ACV-resistant viruses should be further explored.
Viral resistance has been much less of a problem with the two oral antiviral agents approved since lamivudine.
There is an urgent need for the development of new classes of antiviral agents such as SB 9200, that have the potential to reduce viral antigens, eliminate cccDNA, and effect viral clearance.
For them, the drugs of choice remain antiviral agents such as AZT This drug works by blocking the action of an enzyme required by HIV to replicate, or copy, itself.
The urgency of the outbreak has led to the empiric use of broad- spectrum antibiotics and antiviral agents in affected patients in several countries (6-12).
Eventually, physicians switched him to didanosine, another antiviral agent.
A new study suggests that HIV-infected people who have taken zidovudine for at least four months are better off switching to another antiviral agent called didanosine, or DDI.
Food and Drug Administration for entecavir, an investigational antiviral agent under development for the treatment of chronic Hepatitis B.
In late 1984, researchers at the Centers for Disease Control in Atlanta reported that this known antiviral agent was effective in vitro against a virus possibly connected to AIDS (SN: 1/5/85, p.
The company's lead candidate, CMX001, is a Lipid-Antiviral-Conjugate that delivers high intracellular levels of the active antiviral agent cidofovir-diphosphate and has broad spectrum activity against dsDNA viruses in vitro.
The expression of one such immune trigger, interferon gamma, is increased by as much as 20 times, acting as an effective antiviral agent, but without the significant negative clinical side effects of other interferon-based therapies.