In a prior single-agent, Phase 1 clinical study, APTO-253 demonstrated antitumor
activity and a robust safety profile in patients with solid tumors.
torresiana, especially its total flavonoid fraction, has enormous potential as an antitumor
In preclinical studies, two-loaded EC-mAb ADCs demonstrated improved stability and antitumor
activity comparable to traditional four-loaded ADCs in multiple tumor models.
Moreover, the inhibitory rates increased in a dose-dependent manner, indicating that caudatin-2, 6-dideoxy-3-O-methy-[beta]-D-cymaropyranoside and caudatin exhibit significant in vivo antitumor
activity and B-cell depletion have been observed, providing rationale for further dose escalation.
The agent demonstrated broad antitumor
activity against leukemia, melanoma, lung and colon carcinomas in animal models.
Still, scientists must be able to synthesize taxol before they can make other, related antitumor
the natural antitumor
activity of the parental ("unarmed") TAPET in
Pariza's data suggest that a fatty acid in cheese (conjugated linoleic acid) has antitumor
properties (SN: 2/15/92, p.
Biological agents are essential tools in cancer treatment, particularly as antitumor
The patent claims cover methods of stimulating an antitumor
immune response and methods of suppressing tumor growth following the administration of GVAX(TM) cancer vaccine.
Although not designed to assess taxotere's efficacy, the study found the drug had antitumor
effects in six of the 10 women who had ovarian cancer.