antitoxin


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Related to antitoxin: tetanus antitoxin, diphtheria antitoxin, Botulinum antitoxin

antitoxin

 [an´tĭ-tok″sin]
a particular kind of antibody produced in the body in response to the presence of a toxin; see also immunity. adj., adj an´titoxic.
botulism antitoxin an equine antitoxin against the toxins produced by the types A and B and/ or E strains of Clostridium botulinum; administered intravenously in the postexposure prophylaxis and treatment of botulism, other than infant botulism. Generally trivalent (ABE) antitoxin is used.
diphtheria antitoxin equine antitoxin from horses immunized against diphtheria toxin or the toxoid; administered intramuscularly or intravenously in the treatment of suspected cases of diphtheria.
equine antitoxin an antitoxin derived from the blood of healthy horses immunized against a specific bacterial toxin.
tetanus antitoxin equine antitoxin from horses that have been immunized against tetanus toxin or toxoid; used for the passive prevention and treatment of tetanus. It is rarely used, tetanus immune globulin being preferred.

an·ti·tox·in

(an'tē-tok'sin),
Antibody formed in response to antigenic poisonous substances of biologic origin, such as bacterial exotoxins (for example, those elaborated by Clostridium tetani or Corynebacterium diphtheriae), phytotoxins, and zootoxins; in general usage, antitoxin refers to whole, or globulin fraction of, serum from people or animals (usually horses) immunized by injections of the specific toxoid. Antitoxin neutralizes the pharmacologic effects of its specific toxin in vitro, and also in vivo if the toxin is not already fixed to the tissue cells.
[anti- + G. toxikon, poison]

antitoxin

/an·ti·tox·in/ (an´te-) (an´ti-tok″sin) antibody produced in response to a toxin of bacterial (usually an exotoxin), animal (zootoxin), or plant (phytotoxin) origin, which neutralizes the effects of the toxin.an´titoxic
botulism antitoxin  an equine antitoxin against toxins of the types A and B and/or E strains of Clostridium botulinum.
diphtheria antitoxin  equine antitoxin from horses immunized against diphtheria toxin or the toxoid.
equine antitoxin  an antitoxin derived from the blood of healthy horses immunized against a specific bacterial toxin.
tetanus antitoxin  equine antitoxin from horses that have been immunized against tetanus toxin or toxoid.

antitoxin

(ăn′tē-tŏk′sĭn, ăn′tī-)
n.
1. An antibody formed in response to and capable of neutralizing a specific toxin of biological origin.
2. An animal or human serum containing antitoxins. It is used in medicine to prevent or treat diseases caused by the action of biological toxins, such as tetanus, botulism, and diphtheria.

antitoxin

[-tok′sin]
Etymology: Gk, anti + toxikon, poison
a subgroup of antisera usually prepared from the serum of horses immunized against a particular toxin-producing organism, such as botulism antitoxin given therapeutically in botulism and tetanus and diphtheria antitoxins given prophylactically to prevent those infections.

antitoxin

Immunology An antibody-rich serum from an animal stimulated with specific antigens or bacterial toxins–eg, botulinus, tetanus or diphtheria, which is used to provide passive immunity. See Passive immunity.

an·ti·tox·in

(an'tē-tok'sin)
Antibody formed in response to antigenic poisonous substances of biologic origin (e.g., bacterial exotoxins, phytotoxins, and zootoxins); in general usage, serum from humans or animals (usually horses) immunized by injections of the specific toxoid. Antitoxin neutralizes the pharmacologic effects of its specific toxin.
[anti- + G. toxikon, poison]

antitoxin

An ANTIBODY formed by the immune system in response to the presence of TOXIN, produced by bacteria.

antitoxin

a type of ANTIBODY that neutralizes TOXINS.

Antitoxin

An antibody that is capable of neutralizing the specific toxin (a specific cause of disease) that stimulated its production in the body and is produced in animals for medical purposes by injection of a toxin or toxoid with the resulting serum being used to counteract the toxin in other individuals.

antitoxin,

n a substance used to counter directly the effects of a toxin. May be produced by the body or administered from outside the body.

an·ti·tox·in

(an'tē-tok'sin)
Antibody formed in response to antigenic poisonous substances of biologic origin; in general usage, antitoxin refers to whole, or globulin fraction of, serum from people immunized by injections of the specific toxoid.
[anti- + G. toxikon, poison]

antitoxin (an´tētok´sin),

n a subgroup of antisera usually prepared from the serum of horses immunized against a particular toxin-producing organism, such as botulism antitoxin and diphtheria antitoxin given prophylactically to prevent those infections.

antitoxin

a particular kind of antibody produced in the body in response to the presence of a toxin or toxoid. Most commonly used in the treatment of diseases caused by clostridial toxins, e.g. botulinum and tetanus. See also immunity.

gas gangrene antitoxin
serum containing antitoxic antibodies; prepared from the blood of healthy animals immunized against gas-producing organisms of the genus Clostridium.
tetanus antitoxin
preparation from the blood serum or plasma of healthy animals immunized against tetanus toxin. Used for prophylaxis after injury because of its immediate effect. Active immunization is preferred for long-term protection, particularly for many clostridial diseases such as tetanus.
References in periodicals archive ?
Titration of Clostridium welchii epsilon-toxin and antitoxins.
With the structures determined, researchers can now test possible drugs that might force the antitoxin to remain unbound to the toxin, thereby leaving the toxin free to attack its own bacteria.
Contributions to the knowledge of the toxin and antitoxin of Bacilius botulinus.
Feces is added to a cell culture system, and the laboratory analyzes whether a demonstrated cytotoxic effect is neutralized by a specific antitoxin.
Later studies showed that laboratory animals injected with a serum derived from horses with chronic grass sickness were protected from the bacillus botulinum toxin, suggesting that antitoxins - `defensive' proteins developed in response to exposure to a disease - present in the serum were responsible for the protection.
He demonstrated the maneuver of simultaneously pulling down a gas mask and jabbing his thigh with a hypodermic of antitoxin as the chemicals explode in mid-air.
Years of research were spent in establishing an effective diphtheria antitoxin and quantitating its strength, thus leading to the development and standardization of a practical serum.
The Herald's persistent drive to raise money for the production and distribution of antitoxin made diphtheria control a public health program "that disparate .
The charity was founded in America in 1956 by Dr Marion Collins and his wife Chrissie after their daughter, Linda, almost died from a reaction to a sensitivity test for tetanus antitoxin.
In Spite of Your Doctor about tetanus "booster" shots, "Today, I question whether booster shots are ever needed and even whether the administration of tetanus antitoxin makes any sense.
He accomplished his goal within a year, and, in the early summer of 1895, Mulford was able to offer for sale the first commercial diphtheria antitoxin produced in the U.