Antithrombin (redirected from antithrombin III (AT III))

antithrombin /an·ti·throm·bin/ (-throm´bin) any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation.

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antithrombin I  fibrin, referring to its capacity to adsorb thrombin and thus neutralize it.

antithrombin III  a plasma a of the serpin family that inactivates thrombin and also inhibits certain coagulation factors and kallikrein. Inherited deficiency is associated with recurrent deep vein thrombosis and pulmonary emboli; the complications are prevented and treated with a preparation of antithrombin III from pooled human plasma.

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an·ti·throm·bin (nt-thrmbn, nt-)

n.

An anticoagulant that inhibits or prevents the effects of thrombin.

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Antithrombin

Any substance that counters the effect of thrombin, an enzyme that converts fibrinogen into fibrin, leading to blood coagulation.

Mentioned in: Hypercoagulation Disorders

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antithrombin

any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation.

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antithrombin III (AT III)

an alpha₂-globulin synthesized in the liver which is a natural inhibitor of clotting.