antithrombin /an·ti·throm·bin/ (-throm´bin) any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation.
Antithrombin
antithrombin
antithrombin I fibrin, referring to its capacity to adsorb thrombin and thus neutralize it.
antithrombin III a plasma α of the serpin family that inactivates thrombin and also inhibits certain coagulation factors and kallikrein. Inherited deficiency is associated with recurrent deep vein thrombosis and pulmonary emboli; the complications are prevented and treated with a preparation of antithrombin III from pooled human plasma.
an·ti·throm·bin ( n t -thr m b n, nt -)n. An anticoagulant that inhibits or prevents the effects of thrombin. |
Antithrombin
Any substance that counters the effect of thrombin, an enzyme that converts fibrinogen into fibrin, leading to blood coagulation.
Mentioned in: Hypercoagulation Disorders
antithrombin
[-throm′bin]
a substance that inhibits the action of thrombin.
antithrombin
any naturally occurring or therapeutically administered substance that neutralizes the action of thrombin and thus limits or restricts blood coagulation.
antithrombin III (AT III)
an alpha2-globulin synthesized in the liver which is a natural inhibitor of clotting.
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