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antiserum |
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antiserum /an·ti·se·rum/ (an´tĭ-se″rum) a serum containing antibody(ies), obtained from an animal immunized either by injection of antigen or by infection with microorganisms containing antigen.
antiserum [an′tisir′əm] pl. antisera, antiserums Etymology: Gk, anti + L, whey the serum of an animal or human containing antibodies against a specific disease, used to confer passive immunity to that disease. Antisera do not provoke the production of antibodies. There are two types of antisera: antitoxin neutralizes the toxin produced by specific bacteria but does not kill the bacteria, and antimicrobial serum acts to destroy bacteria by making them more susceptible to leukocytic action. Polyvalent antiserum acts on more than one antigenic determinant; monovalent antiserum acts on only one. Antibiotic drugs have largely replaced antimicrobial antisera. Caution must always be used in the administration of all antisera, since hepatitis or hypersensitivity reactions can result. Also called immune serum. Compare vaccine. antiserum a serum containing antibodies. Obtained from an animal that has been exposed to antigen. Used in the prevention, treatment or diagnosis of infectious disease. See also immunity and immunization. antiserum Immunology A serum that contains Igs against specified antigens, used therapeutically How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Rotaviruses can be serotyped by using neutralization assays with panels of antisera and genotyped by type-specific primer-dependent reverse transcription-PCR (RT-PCR) and nucleotide sequence analysis (11-13). Both antisera exhibited 100% cross-reactivity to [E. Some people buy commercial antisera, while others make their own. |
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