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antisense strand

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antisense strand,
the strand of a double-stranded nucleic acid that is complementary to the sense strand, in DNA being the template strand on which the mRNA is synthesized. Compare sense strand.

strand [strand]
a thread or fiber or a structure resembling one.
antisense strand the strand of a double-stranded nucleic acid that is complementary to the sense strand; in DNA it is the template strand on which the mRNA is synthesized.
sense strand the strand of a double-stranded nucleic acid that encodes the product; in DNA it is the strand that encodes the RNA, having thus the same base sequence except changing T for U in the RNA. See also antisense strand.

antisense strand
one of the two strands in a DNA molecule that is not transcribed.


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The thermo-stability bias at the 5' end of the antisense strand: Since it is desirable to have only the antisense strand incorporated into the RISC complex, lowering the thermo-stability at the 5' end of the antisense strand can promote helicase unwind siRNA duplexes from this end [17,20,21].
In this technique, a complementary strand of RNA, the antisense strand, binds to part of a cell's normal, single-stranded RNA.
5' C A U G 3' mRNA 3' G U A C 5' Antisense RNA The second strand is called the antisense strand because its sequence of nucleotides is the reverse complement of message sense.
 
 
 
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