antisense DNA


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an·ti·sense DNA

the strand of DNA complementary to the one bearing the genetic message and from which it may be reconstructed; a DNA sequence complementary to a portion of mRNA; used as potential therapeutic agent to stop transcription or translation of pathogens or inappropriately expressed host gene.
References in periodicals archive ?
On the other path, biochemists are synthesizing small pieces of antisense DNA in the laboratory that match known sequences of DNA.
MG98 -- A 2nd generation antisense DNA compound, currently in Phase II in various cancers.
He also made the first presentation entitled, "Molecular Consequences of Antisense DNA and RNA Knockout of Bcl-2 and Bclxl.
He will also make the first presentation entitled "Molecular Consequences of Antisense DNA and RNA Knockout of Bcl-2 and Bclxl.
The company also announced that it has increased the depth of its HIV/AIDS treatment pipeline to include two proprietary HIV-Hemopurifier(TM) treatments: AEMD-45, which is an immobilized antibody treatment cartridge, and AEMD-61, a treatment cartridge that immobilizes both antibodies for HIV and antisense DNA.
Our objective will be to develop further the ability of Transcell's permeation enhancers to transport antisense DNA compounds across both cellular and mucosal membranes to specific sites within the cell so as to facilitate their potential applications as anti-HIV and anti-AIDS treatments," added Tallett.