Many literatures reported that the compounds contain acyl urea group displayed broad activities, such as anticonvulsant , FAAH inhibitors , antinociceptive , anticancer , antischistosomal
, S1P(2) antagonist activity .
and hepatoprotective activity of Morus alba leaves extract.
The role of parenteral antischistosomal
therapy in the spread of hepatitis C virus in Egypt.
Molluscicidal and antischistosomal
activities of methanol extracts and isolated compounds from Eucalyptus globulus and Melaleuca styphelioides.
The hepatitis C epidemic in Egypt began during 1960-1980, when mass campaigns were conducted to control schistosomiasis through parenteral antischistosomal
therapy (PAT) administered by health-care workers using improperly sterilized glass syringes (5).
The high prevalence of hepatitis C among people born in Egypt can be attributed to a history of parenteral antischistosomal
therapy (PAT) (Frank et al.
Most of those studies used antischistosomal
drugs other than praziquantel.
and antimicrobial activities of some Egyptian plant species.
The current study demonstrated that administration of N sativa crushed seeds to mice harboring S mansoni have shown potential antischistosomal
activity against the different developmental stages of thee parasites, immature larveae (schistosomula, < 14 days Pi, G3), during schistosomula maturation (14-21 days PI,G4), at the time of schistosomula maturation (>21days PI,G5) and after the beginning of egg laying (>35 days PI,G6) (Davies et al.
Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal
Schistosoma mansoni, Biochemical characteristics of the antischistosomal
effects of RD.
mansoni and this stress was significantly reduced by MLE treatment indicating to its antioxidant properties and antischistosomal