antipruritic


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antipruritic

 [an″te-, an″ti-proo-rit´ik]
1. preventing or relieving itching.
2. an agent that so acts.

an·ti·pru·rit·ic

(an'tē-prū-rit'ik),
1. Preventing or relieving itching.
2. An agent that relieves itching.

antipruritic

/an·ti·pru·rit·ic/ (-proo-rit´ik) preventing or relieving itching, or an agent that does this.

antipruritic

(ăn′tē-pro͝o-rĭt′ĭk, ăn′tī-)
adj.
Preventing or relieving itching.
n.
An antipruritic drug.

antipruritic

[-proo͡rit′ik]
Etymology: Gk, anti + L, prurire, to itch
1 pertaining to a substance or procedure that tends to relieve or prevent itching.
2 an antipruritic drug. Topical anesthetics, corticosteroids, and antihistamines are used as antipruritic agents.

antipruritic

adjective Relieving or preventing itching.
 
noun An agent that prevents or relieves itching.

antipruritic

adjective Relieving or preventing itching noun An agent that prevents or relieves itching

an·ti·pru·rit·ic

(an'tē-prūr-it'ik)
1. Preventing or relieving itching.
2. An agent that relieves itching.

antipruritic

Any drug or other treatment effective in relieving itching.

antipruritic

topical agent preventing or relieving itching, i.e. decreasing sensitivity of local nerve endings (e.g. benzocaine), reducing local oedema (e.g. weak iodine solution; menthol; methyl salicylate), cooling skin (e.g. calamine lotion; kaolin powder; hamamelis water; cooling lotions; evaporating lotions) and counteracting histamine release (e.g. antihistamine cream, crotamiton creams [Eurax]) (Table 1 and see Table 2)
Table 1: Topical antipruritic and analgesic agents
AgentAction and usage
Benzocaine; 20% ointmentTreatment of painful heloma neurovasculare
Antipruritic in treatment of chilling
Menthol 2%Dusting powder
Menthol 10%In methyl salicylate ointment; used to reduce inflammation, e.g. hyperaemic phase of chilblains
KaolinDusting powder
Tetracaine 4% gel Ametop gel; Amethocaine 2% creamantipruritic and analgesic
Crotamiton 10% creamEurax: powerful and rapid antipruritic
Mepyramine maleate 2% creamAnthisan: rapidly antipruritic, for insect bites
Table 2: Topical dusting powders for use on skin
Base agents
Starch, Chalk, Magnesium carbonate, Kaolin, Talc, Zinc oxide, Zinc stearate The base agent should augment the action of the active ingredient
Active ingredients
ExamplesActionIndicated use
Boric acid 5%
Salicylic acid 3-10%
Alum 10%
Benzocaine 10%
Calamine
Chlorphensin 1%
Menthol 2%
Phenol 2.5%
Sodium perborate 15%
Sodium poly-metaphosphate 5%
Benzoin 10%
Undecenoic acid 2%
Zinc undecenoate 10%
Active against foetid bacteria
Astringent, antiseptic, antifungal
Strongly astringent and deodorant
Analgesic and antipruritic
Soothing, absorbent
Fungicidal
Fungicidal
Antipruritic and fungicidal
Antiseptic
Astringent
Astringent
Fungicidal
Fungicidal
Bromidrosis
Hyperhidrosis and mild fungal skin infection
Hyperhidrosis and bromidrosis
Irritant skin conditions
Irritant skin conditions
Fungal infections
Fungal infections
Irritant fungal infections
Mild skin infection
Prophylaxis of fungal infection
Hyperhidrosis
Fungal infection
Fungal infection

an·ti·pru·rit·ic

(an'tē-prūr-it'ik)
1. Preventing or relieving itching.
2. An agent that relieves itching.

antipruritic (an´tīprōōrit´ik),

adj relieving or preventing itching.

antipruritic

1. preventing or relieving itching.
2. an agent that counteracts itching; of special importance in the treatment of animals because of the self-trauma that results from their responses to pruritus.
References in periodicals archive ?
Draelos Z, RD047-26 Antipruritic Hydrogel for the Treatment of Atopic Dermatitis: An Open-Label Pilot Study; in press.
Key words: antipruritic, itch, scratch, compound 48/80, Matricaria recutita, Compositae
Thus, the development of non-anti-histamine oral antipruritic drugs or functional foods is highly anticipated.
1984), compound 48/80-induced itch-scratch responses in ddY mice seem to be a suitable parameter for evaluating non-anti-histamine antipruritic agents.
In this report, we examined the antipruritic effect of German chamomile extract using the compound 48/80-induced scratching model in ddY mice.
To examine the antipruritic effect of German chamomile flower, mice were fed the diet containing 30 w/w% of fine powdered dried German chamomile flower for 11 days, and the compound 48/80 (22.
To understand the characteristics of antipruritic activity in German chamomile flower, the effects of various extracts of German chamomile flower were examined (Table 2a, 2b).
Thus the dietary intake of the German chamomile ethyl acetate extract exerted marked antipruritic effects on compound 48/80-induced itch-scratch responses comparable to oxatomide.
4), we supposed the existence of the inhibitory factors on the antipruritic activity of German chamomile flower.
For patients who have prurigo nodularis, thalidomide may be particularly effective as an antipruritic.
Use of agents that contain both moisturizers and topical antipruritics (such as pramoxine) or topical aspirin and salicylates with topical steroids, may be especially useful.