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antiprogestin

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antiprogestin /anti·pro·ges·tin/ (an″te-) (an″ti-pro-jes´tin) a substance that inhibits the formation, transport, or action of progestational agents.
antiprogestin
[-prōjes′tin]
a substance that interferes with the production, uptake, or effects of progesterone. The most common example is mifepristone.


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Progestin and antiprogestin interactions with progesterone receptors in human myomas.
Mifepristone, an antiprogestin, prevents the lining of the uterus from holding onto the fertilized egg, which leads to embryonic demise.
Proellex, the Company's lead compound is an antiprogestin currently being studied in a Phase 2 clinical trial for the treatment of uterine fibroids, a condition that affects approximately 13 million women in the U.
 
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