A partial list of current unmet medical needs Selection & Monitoring Efficacy of Antiplatelet Drugs
(Personalized or Precision Medicine) Genomic Response Classification (hypo, normo, hyer responder) Monitoring Dual Anti Platelet Therapy Verifying Patient Compliance with Drug Therapy Assessing Residual Platelet Reactivity Risk Assessments (Bleeding, Thrombosis) Activity in Oncology and Infectious Disease Patients Table 3.
emblica was not demonstrated in a robust clinical trial, and the risk of pharmacodynamic interaction if used with the common antiplatelet drugs
like clopidogrel or ecosprin were not established.
This modulating effect of antiplatelet drugs
on the efficacy of B vitamins might be explainable by the observation that the adverse effect of homocysteine on the cardiovascular system is mediated in part by increased platelet aggregation.
Determinants of the interindividual variability in response to antiplatelet drugs
Among the drugs implicated most were non-steroidal anti-inflammatory drugs, antiplatelet drugs
, such as low-dose aspirin, epilepsy drugs, drugs to lower blood sugar; water pills (diuretics), and drugs for angina (beta blockers).
, largely low-dose aspirin, have small to moderate benefits when used for the prevention of preeclampsia, reported Dr.
The survey assessed the Impact of Patent Expiration on several key drugs categories such as Antipsychotic drugs, Antibiotics, ADHD drugs, Antacid drugs, Antiplatelet drugs
, Asthma drugs, Diabetes drugs, Arthritis drugs, HIV drugs, Epilepsy drugs, and Cardiovascular drugs.
Further, antiplatelet drugs
often must be stopped five to seven days or more before an operation for antiplatelet activity to return to normal, which extends the amount of time patients are off of DAPT and increases the risk for an adverse cardiac event.
However another aspect of the study, which was the largest one of its kind, demonstrated that patients who took antiplatelet drugs
, such as aspirin, prior to surgery lowered their risk of ischaemic stroke in the first six weeks by 70%.
At discharge the patient was indefinitely medicated with betablockers, angiotensin converting enzyme inhibitors, diuretic and antiplatelet drugs
3-7) The introduction of newer antiplatelet drugs
as well as generic versions of clopidogrel, following Plavix's loss of patent protection on May 17, 2012, changes the economic incentives that are associated with managing these risks.
While even some of the best-managed patients will suffer a serious hemorrhage from taking warfarin or antiplatelet drugs
, the risk of a major bleeding episode from nutritional anticoagulants such as garlic, fish oil, vitamin E, vitamin B6, and nattokinase appears to be remote.