antiparkinsonian

antiparkinsonian

 [an″te-, an″ti-pahr″kin-so´ne-an]
1. effective in treatment of parkinsonism.
2. an agent that has this property.

antiparkinsonian

/an·ti·par·kin·so·ni·an/ (-pahr″kin-so´ne-an) effective in treatment of parkinsonism, or an agent with this quality.

antiparkinsonian

[-pär′kənsōnē·ən]
pertaining to a substance or procedure used to treat parkinsonism. Drugs for this neurological disorder are of two kinds: those that compensate for the lack of DOPamine in the corpus striatum and anticholinergic agents that counteract the activity of the abundant acetylcholine in the corpus striatum. Synthetic levodopa, a DOPamine precursor that crosses the blood-brain barrier, reduces the rigidity, sluggishness, dysphagia, drooling, and instability characteristic of the disease but does not alter its relentless course. Centrally active cholinergic blockers, notably benztropine mesylate, biperiden hydrochloride, procyclidine hydrochloride, and trihexyphenidyl hydrochloride, may relieve tremors and rigidity and improve mobility. The antiviral agent amantadine hydrochloride is often effective in the treatment of parkinsonism; its mechanism of action is not established, but it apparently increases release of DOPamine in the brain. Therapeutic approaches to the relief of the symptoms of parkinsonism include alcohol injection, cautery, cryosurgery, and surgical excision performed to destroy the globus pallidus (reducing rigidity) and parts of the thalamus (reducing tremor). Extrapyramidal symptoms similar to those of idiopathic parkinsonism are frequently induced by antipsychotic drugs.

antiparkinsonian

(ant″i-par″kĭn-sō′nē-ăn) [ anti- + parkinsonian]
1. Effective against parkinsonism.
2. An agent effective against parkinsonism.
References in periodicals archive ?
We used MSA computerized databases (2006-2007) to identify district residents who bought at least one antiparkinsonian drug (code N04 of the Anatomical Therapeutic Chemical Classification System) and/or who received free medical care for PD (Moisan et al.
Quantity: Lot 12 (193 items): Lot 1 medicine that affects the digestive system and metabolism -21 name; Lot 2 drugs that Blood and blood forming organs -22 name; Lot 3 MEDICINES AFFECTING THE CARDIOVASCULAR SYSTEM - 34 name; Lot 4 medication with hormones or content ANTYBIOTYKIV- 12 names; Lot 5 MEDICATIONS psychotropic and narcotic - 4 designation; Lot 6 MEDICINES AFFECTING musculoskeletal-8 names; Lot 7, medicine, Nervous system - 10 items; Lot 8 MEDICINES Antiepileptic and antiparkinsonian - 22 name; Lot 9 -28 MEDICATIONS psycholeptic names; Lot 10 drug-Psychos -18 items; Lot 11 OTHER MEDICINES THAT nervous system -7 names; Lot 12 medicines for respiratory SYSTEMU- 7 items; closing date:19/06/2015
Amantadine (Symmetrel) is a drug that was approved by the US Food and Drug Administration for use as an antiviral and an antiparkinsonian drug, and has been used by Chinese poultry farmers to protect birds against avian influenza.
Since 1986 the not-for-profit PSG has partnered with industry, government and philanthropic institutions to conduct over 40 PD clinical studies, enrolling over 7,000 subjects and contributing to regulatory approval of four antiparkinsonian therapeutics.
However, we attempted to proactively address this by performing exercise and study evaluations while the subjects were within 3 h of antiparkinsonian medication administration.
Blockade of cannabinoid type 1 receptors augments the antiparkinsonian action of levodopa without affecting dyskinesias in 1-methyl-4-phenyl-1.
2005) Motor cortex dysfunction revealed by cortical excitability studies in Parkinson's disease: influence of antiparkinsonian treatment and cortical stimulation.
Recently, some new substituted pyrimidine derivatives have been synthesized, which exhibit analgesic, anti-inflammatory, antiparkinsonian and androgenic-anabolic activities [18-23].
Amantadine has been used as an antiparkinsonian drug since 1969 [11].
1% of the cohort developed PD during the study period, as ascertained from their filling of at least two monthly prescriptions for an antiparkinsonian medication.
However, we would like to underline the importance of monitoring Hcy levels during L-dopa treatment and of starting Hcy-lowering therapy or changing L-dopa with other antiparkinsonian agents in case of hyperhomocysteinemia.
Nightmares are common after sudden withdrawal of REM-suppressant drugs and can also occur as side effects of certain medications, such as antiparkinsonian drugs, anticholinergics, and beta blockers.