antiparkinsonian

antiparkinsonian

 [an″te-, an″ti-pahr″kin-so´ne-an]
1. effective in treatment of parkinsonism.
2. an agent that has this property.

antiparkinsonian

/an·ti·par·kin·so·ni·an/ (-pahr″kin-so´ne-an) effective in treatment of parkinsonism, or an agent with this quality.

antiparkinsonian

[-pär′kənsōnē·ən]
pertaining to a substance or procedure used to treat parkinsonism. Drugs for this neurological disorder are of two kinds: those that compensate for the lack of DOPamine in the corpus striatum and anticholinergic agents that counteract the activity of the abundant acetylcholine in the corpus striatum. Synthetic levodopa, a DOPamine precursor that crosses the blood-brain barrier, reduces the rigidity, sluggishness, dysphagia, drooling, and instability characteristic of the disease but does not alter its relentless course. Centrally active cholinergic blockers, notably benztropine mesylate, biperiden hydrochloride, procyclidine hydrochloride, and trihexyphenidyl hydrochloride, may relieve tremors and rigidity and improve mobility. The antiviral agent amantadine hydrochloride is often effective in the treatment of parkinsonism; its mechanism of action is not established, but it apparently increases release of DOPamine in the brain. Therapeutic approaches to the relief of the symptoms of parkinsonism include alcohol injection, cautery, cryosurgery, and surgical excision performed to destroy the globus pallidus (reducing rigidity) and parts of the thalamus (reducing tremor). Extrapyramidal symptoms similar to those of idiopathic parkinsonism are frequently induced by antipsychotic drugs.

antiparkinsonian

(ant″i-par″kĭn-sō′nē-ăn) [ anti- + parkinsonian]
1. Effective against parkinsonism.
2. An agent effective against parkinsonism.
References in periodicals archive ?
Such medications include diuretics, beta-blockers, alpha adrenergic blockers, vasodilators, antipsychotics, antidepressants (SSRIs, trazodone, monoamine oxidase inhibitors, and tricyclic antidepressants), phosphodiesterase inhibitors, narcotics, and antiparkinsonian medications.
Caffeine is a nonspecific AR antagonist that has shown antiparkinsonian and neuroprotective effects in animal models of PD.
In these patients, the postoperative risks are determined with the presence of additional diseases, interaction of antiparkinsonian medication and anesthesic drugs.
This study included IPD patients who received regular antiparkinsonian therapy and were followed in the Motor Disorders Outpatient Clinic of the Neurology Department of the Bezmialem Vakif University School of Medicine between April 13 and July 02, 2015.
Anticonvulsants and antiparkinsonian drugs must be maintained up until a few hours prior to the procedure (6).
Patient A was under ART with tenofovir (TDF), lamivudine (3TC), atazanavir (ATV) and ritonavir (r), had no cognitive complaints and a last reported Mini Mental State Exam (MMSE) of 29/30; he had mild bilateral bradykinesia in upper extremities and postural, rest and kinetic tremor in the right arm that did not interfere with activities of daily living and therefore was not on any antiparkinsonian drug.
Consequences of nonadherence or suboptimal use of antiparkinsonian medication could lead to lack of efficacy, increased symptoms, premature treatment modifications, or poor outcomes such as an increased risk of dyskinesia and decreased quality of life (Grosset et al.
Treatment with antiparkinsonian drugs like dopamine agonist has been avoided in clinical practice due to their potential to worsen psychosis, but in 2014, Bhandari R and Agarwal A.
Parkinsonism or drug drug interactions with the antiparkinsonian medications may have predisposed this patient to serotonin syndrome at such low doses of Venlafaxine.
Use of carnosine reduced toxic effects of basic therapy (side effects of antiparkinsonian agents).
GID usually appears 6 to 24 months after grafting, despite cessation of antiparkinsonian medications [20].