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antioxidant therapy

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antioxidant therapy
Therapeutics A general term for the use of any agent–eg, antioxidant vitamins, glutathione reductase, superoxide dismutase, to 'scavenge' O2 free radicals–OFRs or excited O2 molecules, which are by-products of normal metabolic reactions; excess OFRs have been linked to cancer 2º to OFR-induced DNA damage, and to cardiovascular disease 2º to OFR-induced oxidation of LDL-cholesterol to a more atherogenic form; in cardiology, AT attempts to block the oxidative modification of LDL, which is thought to be an early step in fatty streak development, atherogenesis and ASHD-related pathologies–eg, CAD and CVAs. See Antioxidant, Antioxidant vitamin.


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