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antineutrophil cytoplasmic antibody |
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antineutrophil cytoplasmic antibody ANCA Immunology Any autoantibody directed against certain components of granulocytes, myeloid-specific lysosomal enzymes; ANCAs are most commonly found in systemic vasculitides–eg, necrotizing
vasculitis, active generalized Wegener's granulomatosis–WG, 84-100% are positive, polyarteritis nodosa, inflammatory conditions of the lung and kidney–eg, crescentic glomerulonephritis, unexplained renal failure, Churg-Strauss
syndrome, HIV infection, IBD, drug-induced lupus, SLE, rheumatoid arthritis, and others How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Ideally, evaluation should include a biopsy, measurement of the antineutrophil cytoplasmic antibody (e-ANCA) level, and other laboratory evaluations to rule out sarcoidosis and autoimmune disease. Measurements of the complete blood count, erythrocyte sedimentation rate, antineutrophil cytoplasmic antibody (ANCA) level, and antinuclear antibody (ANA) level were all within normal ranges. |
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