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antimitotic agent

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antimitotic agent
Antimicrotubule agent, mitotic inhibitor Oncology An agent that inhibits cancer growth by stopping cell division Pharmacology A drug that inhibits or blocks mitosis in a particular phase of the cell cycle–eg, metaphase arrest caused by colchicine and vinca alkaloids. See Chemotherapy.


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ENMD-1198, a novel antimitotic agent, and ENMD-2076, a selective kinase inhibitor, are in Phase 1 studies in advanced cancers.
They act as antimitotic agents in the epidermis by influencing gene transcription resulting in inhibition of the immunological, inflammatory and proliferative processes of the disease [14-16].
The decreasing MI rates in peripheral blood lymphocytes indicate that propolis may be an anticarcinogenic and also antimitotic agent.
 
 
 
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