antimitotic agent


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antimitotic agent

Oncology
An agent that inhibits cancer growth by inhibiting cell division.
 
Pharmacology
A drug that inhibits or blocks mitosis in a particular phase of the cell cycle (e.g., metaphase arrest caused by colchicine and vinca alkaloids).

antimitotic agent

Antimicrotubule agent, mitotic inhibitor Oncology An agent that inhibits cancer growth by stopping cell division Pharmacology A drug that inhibits or blocks mitosis in a particular phase of the cell cycle–eg, metaphase arrest caused by colchicine and vinca alkaloids. See Chemotherapy.
References in periodicals archive ?
Synthesis of a new 4-aza2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents.
They act as antimitotic agents in the epidermis by influencing gene transcription resulting in inhibition of the immunological, inflammatory and proliferative processes of the disease [14-16].
Antimitotic agents, used alone or most commonly in combination, continue to be an important part of cancer therapy; AMRI's tubulin inhibitor has potential to broaden this current arsenal.
An Aden carcinoma is involved in the majority of such cases, but in most cases it is actually the antimitotic agents that are at fault (mitomycin C, 5-fluorouracil, platinum-based drugs and bleomycin).