antimitotic


Also found in: Dictionary.
Related to antimitotic: antiemetic, colchicine, telangiectasia

an·ti·mi·tot·ic

(an'tē-mī-tot'ik),
1. Having an arresting action on mitosis.
2. A drug having such an effect; for example, a folic acid antagonist that is used in leukemia to inhibit the multiplication of white blood cells.

antimitotic

(ăn′tē-mī-tŏt′ĭk, ăn′tī-)
adj.
Preventing or interfering with mitosis.
n.
An antimitotic drug.

antimitotic

[-mītot′ik]
inhibiting cell division.

antimitotic

adjective Referring to an agent or mechanism that inhibits mitosis—i.e., the multiplication of cancer cells.

noun An agent used to manage cancer that acts by inhibiting cell division.

an·ti·mi·tot·ic

(an'tē-mī-tot'ik)
Inhibiting the process of mitosis.

antimitotic

1. Anything which interferes with cell division.
2. An anticancer drug, or agency, which acts by interfering with the reproduction of cancer cells.
References in periodicals archive ?
argentea is an indication of cytotoxicity, whereas the antimitotic activity of the aqueous extracts of C.
Based on the obtained results and previous studies can be concluded that such effects of antimitotic drugs (cytotoxic) could include:
Diabetes, renal failure, duration of stent placement, small reference vessel diameter, complex lesions, low ejection fraction, local hypersensitivity reactions, position of the stent relative to plaque, type and dose of antimitotic agent have also been identified as contributory factors (8,10-13).
Flaxseed is a rich source of lignans, which have been shown to affect androgen metabolism and have antimitotic, antiangiogenic, antioxidant, and estrogenic effects.
Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties.
After the antimitotic treatment, the samples were kept for 45 min in a hypotonic solution (seawater: distilled water, 1:1).
The current initial study explores the effect of cisplatin, an antimitotic drug, and PenELP (Penetratin elastin-like polypeptide) on T24 cell growth at different temperatures.
Colchicine possesses potent antimitotic activity due to its ability to bind to tubulin and thereby inhibit the polymerization of tubulin into microtubules.
Antimitotic agents, used alone or most commonly in combination, continue to be an important part of cancer therapy; AMRI's tubulin inhibitor has potential to broaden this current arsenal.
The benzofuroindoline core is a unique motif found in the natural products diazonamide A, a very potent anti-cancer agent ( 5 nM against various cell lines) which may have clinical utility for cancer therapy since it is as active as widespread used antimitotic drugs without their overt toxicity.