antilymphocyte serum

an·ti·lym·pho·cyte serum (nt-lmf-st, nt-)

n.

Abbr. ALS The globulin fraction of serum from a horse or another animal, usually used in conjunction with other immunosuppressive agents to suppress rejection of grafts or organ transplants.

---

antilymphocyte serum

antiserum containing antibodies specific for lymphocyte surface antigens that may be used to suppress delayed type hypersensitivity, particularly graft rejection, responses without affecting humoral immune response; abbreviated ALS. Used in organ transplantation, usually in combination with immunosuppressive drugs. Prepared by hyperimmunizing an animal, e.g. horse, with foreign, e.g. human, lymphocytes. See also antilymphocyte globulin.