antihuman globulin


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an·ti·hu·man glob·u·lin

serum from a rabbit or other animal previously immunized with purified human globulin to prepare antibodies directed against human immunoglobulin, some of which may be used in the direct and indirect Coombs tests.
Synonym(s): Coombs serum

an·ti·hu·man glob·u·lin

(an'tē-hyū'măn glob'yū-lin)
Serum from a rabbit or other animal previously immunized with purified human globulin to prepare antibodies directed against IgG and complement; used in the direct and indirect Coombs tests.
Synonym(s): Coombs serum.

Coombs,

Robin R.A., English veterinarian and immunologist, 1921–.
Coombs serum - serum from a rabbit or other animal previously immunized with purified human globulin to prepare antibodies directed against IgG and complement. Synonym(s): antihuman globulin
Coombs test - a test for antibodies, the so-called antihuman globulin test, using either the direct or indirect Coombs tests. Synonym(s): antiglobulin test
direct Coombs test - a test for detecting sensitized erythrocytes in erythroblastosis fetalis and in cases of acquired immune hemolytic anemia.
Gell and Coombs reaction - see under Gell
indirect Coombs test - a test routinely performed in cross-matching blood or in the investigation of transfusion reaction.
References in periodicals archive ?
Antihuman globulin reagents are the company's largest dollar sales product line.
1-3) To detect anti-HLA antibodies, a complement-dependent cytotoxicity (CDC) panel-reactive antibody (PRA) screening method can be used without (CDC PRA) or with antihuman globulin (AHG; CDC-AHG PRA).
Sensitivity and Specificity of the 6540 Mean Fluorescent Intensity (MFI) Cutoff Value for Class I Donor-Specific Antibody (DSA) Strength in Predicting Positive Complement-Dependent Cytotoxicity Antihuman Globulin T-Cell Crossmatches (CDC-AHG T-Cell XMs) in Proficiency Test and Patient Samples Positive Negative CDC-AHG CDC-AHG Samples, MFI No.