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antihormone

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an·ti·hor·mone (nt-hôrmn, nt-)
n.
A substance that inhibits or that prevents the effects of a hormone.

antihormone
a substance, usually antibody, that counteracts a hormone. It is produced in animals after repeated injections of a hormone or hormone-bearing protein. Further doses of the hormone may result in the neutralization of the hormone, in neutralization of the patient's own hormone, or in stimulation of an attack of allergy or anaphylaxis.

antihormone
Endocrinology A natural or synthetic analogue of a hormone–eg, FSH, LH, which binds to the hormone's receptor, blocking its activity. See B/I ratio.


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Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element, Mol Pharmacol 54:1113-1117.
By binding to gonadal cells, these antagonistic antihormones block activity by well-known forms of FSH, thereby disrupting normal hormone secretion.
 
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