antiglobulin


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antiglobulin

 [an″tĭ-glob´u-lin]
an antibody directed against gamma globulin.
antiglobulin test (AGT) Coombs' test.

antiglobulin

/an·ti·glob·u·lin/ (an″te-) (an″ti-glob″u-lin) an antibody directed against gamma globulin, as used in the antiglobulin test.

antiglobulin

[an′tiglob′yoo͡lin]
Etymology: Gk, anti + L, globulus, small globe
an antibody against gamma globulin. Also called antihuman globulin See also antiglobulin test, precipitin.

an·ti·glob·u·lin

(an'tē-glob'yū-lin)
Antibody that combines with and precipitates globulin.

antiglobulin

an antibody to a heterologous antibody, such as goat antihorse IgG antibody, as used in the Coombs test, ELISA, immunofluorescence or other assays.

antiglobulin test
References in periodicals archive ?
Further laboratory results (direct antiglobulin test and bilirubin) were assessed and reported for five babies whose maternal alloantibody titre by IAT tube was less than 16, but equal to 16 by CAT.
a]-, E-, and M-negative; and crossmatch-compatible by tube method at antiglobulin phase.
Comparison of mixed antiglobulin reaction and direct immunobead test for detection of sperm-bound antibodies in subfertile males.
Abnormalities in platelet antiglobulin tests in preeclamptic mothers and their neonates.
Uninfected erythrocytes bind increased amount of immunoglobulin and/or complement as detected in the direct antiglobulin test (DAT or Coomb's Test) (9,10).
A sensitive assay for the detection of anti-daclizumab antibodies developed by T Waldmann has shown that there is, if at all, very little antiglobulin response to antibody treatment and does not appear to have impact on the biological function of daclizumab.
ATLANTA -- Healthy blood donors with positive direct antiglobulin tests develop cancer more than twice as often as those who test negative, according to a provocative study that linked thousands of blood bank records to Israel's national cancer registry.
1) Regardless of the mechanism of activity and the presence of a positive direct antiglobulin test (DAT), hemolytic anemias caused by drug therapies are rare.
If screening for antibodies had not been done before entry into the programme, a mixed erythrocyte-spermatozoa antiglobulin test (MAR test) was done as a screening procedure to exclude male immunological infertility.
These are IgG- and IgM-mediated disorders that produce positive direct antiglobulin (Coombs') tests that are clinically and serologically indistinct from autoimmune haemolytic anaemia.
The tests were performed by two stage enzyme technique and indirect antiglobulin technique (IAT) (9).
If hemolysis is suspected then a direct antiglobulin test (Coombs test), reticulocyte count and haptoglobin should be checked.